Pulec J L, Pulec M B, Mendoza I
Pulec Ear Clinic and Ear International, Los Angeles, California, USA.
Ear Nose Throat J. 1997 Oct;76(10):716-20, 725-6, 728 passim.
The otologist frequently sees patients with progressive sensorineural hearing loss, subjective aural tinnitus and vertigo with no apparent cause. Elevated blood lipids may be a cause of inner ear malfunction on a biochemical basis. To establish the true incidence of this condition, all new patients (4,251) seen during an eight-year period were evaluated; of these, 2,332 patients had complaints of inner ear disease. All had a complete neurotologic examination, appropriate audiometric and vestibular studies and imaging, and blood tests including lipid phenotype studies. Hyperlipoproteinemia was found in 120 patients (5.1%). Most patients were found to be overweight and had additional coexisting conditions such as diabetes mellitus. Treatment with vasodilators and a 500-calorie, high-protein, low-carbohydrate diet yielded improvement of symptoms in 83% of patients within five months of initiation of treatment.
耳科医生经常会接待一些患有进行性感音神经性听力损失、主观性耳鸣和眩晕但无明显病因的患者。血脂升高可能在生化层面上是内耳功能障碍的一个原因。为了确定这种情况的真实发生率，我们对八年期间接诊的所有新患者（4251例）进行了评估；其中，2332例患者有内耳疾病主诉。所有患者均接受了全面的神经耳科检查、适当的听力测定和前庭研究以及影像学检查，还有包括血脂表型研究在内的血液检查。120例患者（5.1%）被发现患有高脂蛋白血症。大多数患者被发现超重且伴有其他并存疾病，如糖尿病。使用血管扩张剂以及500卡路里、高蛋白、低碳水化合物饮食进行治疗，在开始治疗后的五个月内，83%的患者症状得到改善。
