Department of Radiology, Xuanwu Hospital, Capital Medical University, Beijing, China.
PLoS One. 2013;8(1):e50939. doi: 10.1371/journal.pone.0050939. Epub 2013 Jan 2.
Brain atlases are designed to provide a standard reference coordinate system of the brain for neuroscience research. Existing human brain atlases are widely used to provide anatomical references and information regarding structural characteristics of the brain. The majority of them, however, are derived from one paticipant or small samples of the Western population. This poses a limitation for scientific studies on Eastern subjects. In this study, 10 new Chinese brain atlases for different ages and genders were constructed using MR anatomical images based on HAMMER (Hierarchical Attribute Matching Mechanism for Elastic Registration). A total of 1,000 Chinese volunteers ranging from 18 to 70 years old participated in this study. These population-specific brain atlases represent the basic structural characteristics of the Chinese population. They may be utilized for basic neuroscience studies and clinical diagnosis, including evaluation of neurological and neuropsychiatric disorders, in Chinese patients and those from other Eastern countries.
脑图谱旨在为神经科学研究提供大脑的标准参考坐标系。现有的人类脑图谱被广泛用于提供大脑的解剖学参考和有关结构特征的信息。然而，它们中的大多数是从一个参与者或西方人群的小样本中得出的。这对东方人群的科学研究构成了限制。在这项研究中，使用基于 HAMMER（分层属性匹配弹性配准机制）的 MR 解剖图像，构建了 10 个新的不同年龄和性别的中国脑图谱。共有 1000 名年龄在 18 至 70 岁之间的中国志愿者参与了这项研究。这些特定于人群的脑图谱代表了中国人群的基本结构特征。它们可用于基础神经科学研究和临床诊断，包括评估中国患者和来自其他东方国家的患者的神经和神经精神障碍。
