Department of Chemistry & Biochemistry, University of California, Santa Barbara, California 93106-9510, USA.
Org Lett. 2013 Feb 1;15(3):476-9. doi: 10.1021/ol303263q. Epub 2013 Jan 23.
The first example of a Piancatelli rearrangement of alcohols is demonstrated utilizing dysprosium(III) triflate as a catalyst to access oxaspirocycles in a highly diastereoselective manner. The cascade reaction constructs the spirocyclic ether ring system and the tertiary stereocenter in a single operation and is experimentally easy to perform.
第一个利用醇的 Piancatelli 重排反应的例子是利用三氟甲磺酸镝作为催化剂，以高度非对映选择性的方式获得噁螺环化合物。该级联反应在单个操作中构建了螺环醚环系统和叔立体中心，实验操作简单。
