Rheumatology Unit, Azienda Ospedaliera di Reggio Emilia, IRCCS, Reggio Emilia, Italy.
Clin Exp Rheumatol. 2013 Jan-Feb;31(1 Suppl 75):S3-4. Epub 2013 Jan 23.
To report a patient with Takayasu arteritis in whom 18F-Fluorodeoxyglucose (FDG) positron emission tomography (PET)/computerised tomography (CT) failed to demonstrate pulmonary artery involvement.
A patient with Takayasu arteritis underwent PET/CT and CT angiography before and one year after immunosuppressive treatment.
Before treatment, PET/CT showed increased FDG uptake in the aortic arch and epiaortic arteries; pulmonary arteries were not visualised. Follow-up PET/CT one year later demonstrated resolution of abnormal vascular FDG uptake. CT angiography of the chest/abdomen prior to treatment revealed circumferential thickening of the ascending aorta, aortic arch, supra-aortic branches, and left inferior intralobar pulmonary artery with normal lumen diameter (27 mm). After therapy, CT angiography revealed decreased aortic wall thickening with complete resolution of intralobar wall thickening. However, the lumen of the central pulmonary artery was increased (32 mm).
PET/CT is very sensitive in depicting active vasculitis, but cannot visualise the pulmonary arteries, presumably because their diameter is below the power of detection of PET/CT. CT angiography or magnetic resonance angiography is required to evaluate pulmonary artery abnormalities.
报告一例经 18F-氟脱氧葡萄糖（FDG）正电子发射断层扫描（PET）/计算机断层扫描（CT）未能显示肺动脉受累的 Takayasu 动脉炎患者。
一名 Takayasu 动脉炎患者在免疫抑制治疗前后进行了 PET/CT 和 CT 血管造影检查。
治疗前，PET/CT 显示主动脉弓和主动脉外膜的 FDG 摄取增加；肺动脉无法显示。一年后的随访 PET/CT 显示异常血管 FDG 摄取得到缓解。治疗前的胸部/腹部 CT 血管造影显示升主动脉、主动脉弓、主动脉外分支和左下叶肺段动脉的环形增厚，管腔直径正常（27 毫米）。治疗后，CT 血管造影显示主动脉壁增厚减少，肺段壁增厚完全缓解。然而，中央肺动脉的管腔增大（32 毫米）。
PET/CT 对活动性血管炎的检测非常敏感，但无法显示肺动脉，可能是因为其直径低于 PET/CT 的检测能力。需要进行 CT 血管造影或磁共振血管造影来评估肺动脉异常。
