意大利流行的葡萄球菌克隆中新的利奈唑胺耐药多种机制的令人担忧趋势。
Worrisome trend of new multiple mechanisms of linezolid resistance in staphylococcal clones diffused in Italy.
机构信息
University of Catania, Catania, Italy.
出版信息
J Clin Microbiol. 2013 Apr;51(4):1256-9. doi: 10.1128/JCM.00098-13. Epub 2013 Jan 23.
Abstract
In order to assess the frequency of clinically relevant linezolid-resistant staphylococcal isolates, and the role of linezolid in maintaining and coselecting multiple resistance mechanisms (cfr, 23S rRNA, L3/L4 mutations), a prospective Italian study was performed from 2010 to 2011 to confirm the diffusion of three major multidrug-resistant clones (ST2, ST5, ST23).
摘要
为了评估临床相关的利奈唑胺耐药葡萄球菌分离株的频率，以及利奈唑胺在维持和共同选择多种耐药机制（cfr、23S rRNA、L3/L4 突变）方面的作用，一项前瞻性意大利研究于 2010 年至 2011 年进行，以确认三种主要的多药耐药克隆（ST2、ST5、ST23）的扩散。
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