Department of Pathology and Genomic Medicine, The Methodist Hospital, Houston, Texas, USA.
J Clin Microbiol. 2013 Apr;51(4):1272-7. doi: 10.1128/JCM.03237-12. Epub 2013 Jan 23.
Next-generation sequencing technology is available to many clinical laboratories; however, it is not yet widely used in routine microbiology practice. To demonstrate the feasibility of using whole-genome sequencing in a routine clinical microbiology workflow, we sequenced the genome of every organism isolated in our laboratory for 1 day.
下一代测序技术已在许多临床实验室中得到应用;然而,它尚未在常规微生物学实践中广泛使用。为了证明全基因组测序在常规临床微生物学工作流程中的可行性,我们对实验室在一天内分离的每个生物体的基因组进行了测序。