单个微管组装和解聚模型：随机方程和平均方程
Models of assembly and disassembly of individual microtubules: stochastic and averaged equations.
作者信息
Bolterauer H, Limbach H J, Tuszyński J A
机构信息
Institut für Theoretische Physik, Justus-Liebig Universität Gießen, Gießen, Germany.
出版信息
J Biol Phys. 1999 Mar;25(1):1-22. doi: 10.1023/A:1005159215657.
Abstract
In this paper we present solutions of the master equations for the microtubule length and show that the local probability for rescues or catastrophes can lead to bell-shaped length histograms. Conversely, as already known, non-local probabilities for these events result in exponential length histograms. We also derive master equations for a stabilizing cap and obtain a new boundary condition which provides an explanation of the results obtained in dilution and cutting experiments.
摘要
在本文中，我们给出了微管长度主方程的解，并表明救援或灾变的局部概率可导致钟形长度直方图。相反，如已知的那样，这些事件的非局部概率会导致指数长度直方图。我们还推导了稳定帽的主方程，并获得了一个新的边界条件，该条件解释了在稀释和切割实验中得到的结果。
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