Department of Dermatology, Wayne State University School of Medicine, Detroit, MI, USA.
Clin Interv Aging. 2013;8:29-35. doi: 10.2147/CIA.S31930. Epub 2013 Jan 14.
The most compelling reason and primary goal of treating actinic keratoses is to prevent malignant transformation into invasive squamous cell carcinoma, and although there are well established guidelines outlining treatment modalities and regimens for squamous cell carcinoma, the more commonly encountered precancerous actinic lesions have no such standard. Many options are available with variable success and patient compliance rates. Prevention of these lesions is key, with sun protection being a must in treating aging patients with sun damage as it is never too late to begin protecting the skin.
治疗光化性角化病最有说服力的原因和主要目标是防止恶性转化为侵袭性鳞状细胞癌,虽然已经有明确的指南概述了鳞状细胞癌的治疗方式和方案,但更常见的癌前光化性病变没有这样的标准。有许多可供选择的方法,成功率和患者依从率各不相同。预防这些病变是关键,对于因日晒而受损的老年患者,防晒是必须的,因为保护皮肤永远不会太晚。