Trairatvorakul Chutima, Sastararuji Treesa
Department of Paediatric Dentistry, Faculty of Dentistry, Chulalongkorn University, Bangkok, Thailand.
Int J Paediatr Dent. 2014 Jan;24(1):23-31. doi: 10.1111/ipd.12022. Epub 2013 Jan 24.
Calcium hydroxide indirect pulp treatment (CH-IPT) and antibiotic sterilization using a mixture of three antibiotics (3Mix-MP) of deep caries are similar non-invasive vital pulp treatments. No studies have compared their clinical and radiographic success rates in primary molars.
To compare the clinical and radiographic success rates of CH-IPT and 3Mix-MP in carious lesions approaching the pulp of mandibular primary molars.
Eighty-two mandibular primary molars from 50 children, aged 3-8 years, with carious lesions approaching the pulp, and meeting the inclusion criteria, were randomly assigned for either treatment. After treatment, blinded clinical/radiographic evaluation was performed at 6-11 and 12-29 month recalls.
At 6-11 months, the overall success rates of CH-IPT and 3Mix-MP were 82% and 81% (P = 0.91), respectively. At 12-29 months, the success rates were 94% and 78% (P = 0.08), respectively. The most frequently observed failure at the 12-29 month recall was internal resorption (one CH-IPT tooth and three 3Mix-MP teeth).
There was no statistically significant difference in overall success rates between CH-IPT and 3Mix-MP in treating deep caries approaching the pulp in mandibular primary molars at either 6-11 month or 12-29 month follow-up.
氢氧化钙间接盖髓术（CH-IPT）和使用三种抗生素混合物（3Mix-MP）对深龋进行抗生素消毒是类似的非侵入性活髓治疗方法。尚无研究比较它们在乳牙磨牙中的临床和影像学成功率。
比较CH-IPT和3Mix-MP在下颌乳牙磨牙接近牙髓的龋损中的临床和影像学成功率。
将来自50名3至8岁患有接近牙髓的龋损且符合纳入标准的儿童的82颗下颌乳牙磨牙随机分配接受其中一种治疗。治疗后，在6至11个月和12至29个月复诊时进行盲法临床/影像学评估。
在6至11个月时，CH-IPT和3Mix-MP的总体成功率分别为82%和81%（P = 0.91）。在12至29个月时，成功率分别为94%和78%（P = 0.08）。在12至29个月复诊时最常观察到的失败情况是内吸收（1颗CH-IPT治疗的牙齿和3颗3Mix-MP治疗的牙齿）。
在6至11个月或12至29个月的随访中，CH-IPT和3Mix-MP在下颌乳牙磨牙接近牙髓的深龋治疗中的总体成功率无统计学显著差异。
