Matsui Masaru, Okayama Satoshi, Samejima Kenichi, Saito Yoshihiko
First Department of Internal Medicine, Nara Medical University, Nara, Japan.
BMJ Case Rep. 2013 Jan 24;2013:bcr2012008103. doi: 10.1136/bcr-2012-008103.
A man in his 30s with dilated cardiomyopathy was admitted to our hospital with heart failure exacerbation. Despite optimal medical treatment, his renal function progressively declined to end-stage renal failure. Type 2 cardiorenal syndrome (CRS) was diagnosed and continuous ambulatory peritoneal dialysis was started. He died of a brainstem infarction 4 years later. Postmortem renal pathology revealed no significant changes in the glomeruli except for shrinkage, normal arterioles and focal degeneration of the tubules with peritubular fibrosis. This suggests that renal replacement therapy can be withdrawn from some patients with type 2 CRS.
一名30多岁的扩张型心肌病男性因心力衰竭加重入住我院。尽管接受了最佳药物治疗,但其肾功能仍逐渐恶化至终末期肾衰竭。诊断为2型心肾综合征(CRS),并开始持续非卧床腹膜透析。4年后,他死于脑干梗死。尸检肾脏病理显示,除肾小球萎缩外,肾小球无明显变化,小动脉正常,肾小管局灶性变性伴肾小管周围纤维化。这表明对于一些2型CRS患者可以停止肾脏替代治疗。