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1
Unforeseen renal pathological findings in a patient with type 2 cardiorenal syndrome who died after 4 years of continuous ambulatory peritoneal dialysis.一名2型心肾综合征患者在持续非卧床腹膜透析4年后死亡,出现意外的肾脏病理检查结果。
BMJ Case Rep. 2013 Jan 24;2013:bcr2012008103. doi: 10.1136/bcr-2012-008103.
2
Subtotal nephrectomy accelerates pathological cardiac remodeling post-myocardial infarction: implications for cardiorenal syndrome.次全肾切除术加速心肌梗死后病理性心脏重构:对心肾综合征的影响。
Int J Cardiol. 2013 Oct 3;168(3):1866-80. doi: 10.1016/j.ijcard.2012.12.065. Epub 2013 Jan 22.
3
Peritoneal dialysis allows successful cardiac transplantation in patients with refractory heart failure.腹膜透析使难治性心力衰竭患者成功进行心脏移植成为可能。
Nefrologia. 2015;35(1):121-4. doi: 10.3265/Nefrologia.pre2014.Sep.12570.
4
Cardiorenal syndrome.心肾综合征。
Heart Lung. 2012 Mar-Apr;41(2):157-60. doi: 10.1016/j.hrtlng.2011.06.001. Epub 2011 Jul 23.
5
Peritoneal Dialysis for the Treatment of Cardiorenal Syndrome Type 1: A Prospective Brazilian Study.腹膜透析治疗1型心肾综合征:一项巴西前瞻性研究。
Perit Dial Int. 2017 Sep-Oct;37(5):578-583. doi: 10.3747/pdi.2016.00217.
6
Role of peritoneal dialysis as a chronic renal replacement therapy in cardiorenal patients.腹膜透析作为慢性肾脏替代疗法在心脏-肾脏疾病患者中的作用。
Contrib Nephrol. 2012;178:182-188. doi: 10.1159/000337850. Epub 2012 May 25.
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Peritoneal Dialysis for Chronic Congestive Heart Failure.慢性充血性心力衰竭的腹膜透析
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Nonuremic indication for peritoneal dialysis for refractory heart failure in cardiorenal syndrome type II: review and perspective.非尿毒症患者因心脏-肾脏综合征 II 型难治性心力衰竭而行腹膜透析的适应证:综述与展望。
Perit Dial Int. 2013 Jan-Feb;33(1):8-14. doi: 10.3747/pdi.2012.00014.
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Parameters associated with therapeutic response using peritoneal dialysis for therapy refractory heart failure and congestive right ventricular dysfunction.使用腹膜透析治疗难治性心力衰竭和充血性右心室功能障碍的治疗反应相关参数。
PLoS One. 2018 Nov 19;13(11):e0206830. doi: 10.1371/journal.pone.0206830. eCollection 2018.
10
Inflammation and myocardial damage markers influence loss of residual renal function in peritoneal dialysis patients.炎症和心肌损伤标志物会影响腹膜透析患者残余肾功能的丧失。
Arch Med Res. 2014 Aug;45(6):484-8. doi: 10.1016/j.arcmed.2014.07.003. Epub 2014 Jul 15.

本文引用的文献

1
Cardio-renal syndrome type 2: epidemiology, pathophysiology, and treatment.心肾综合征 2 型:流行病学、病理生理学和治疗。
Semin Nephrol. 2012 Jan;32(1):26-30. doi: 10.1016/j.semnephrol.2011.11.004.
2
Deterioration of renal function by chronic heart failure is associated with congestion and oxidative stress in the tubulointerstitium.慢性心力衰竭导致的肾功能恶化与肾小管间质的充血和氧化应激有关。
Intern Med. 2011;50(23):2877-87. doi: 10.2169/internalmedicine.50.5925. Epub 2011 Dec 1.
3
Cardiorenal syndrome - a new classification and current evidence on its management.心肾综合征——一种新的分类及其管理的当前证据。
Clin Nephrol. 2010 Oct;74(4):245-57. doi: 10.5414/cnp74245.
4
Cardiorenal syndrome.心肾综合征
J Am Coll Cardiol. 2008 Nov 4;52(19):1527-39. doi: 10.1016/j.jacc.2008.07.051.
5
Renal insufficiency as a predictor of cardiovascular outcomes and the impact of ramipril: the HOPE randomized trial.肾功能不全作为心血管结局的预测因素及雷米普利的影响:心脏结局预防评估(HOPE)随机试验
Ann Intern Med. 2001 Apr 17;134(8):629-36. doi: 10.7326/0003-4819-134-8-200104170-00007.
6
The clinical epidemiology of cardiac disease in chronic renal failure.慢性肾衰竭中心脏疾病的临床流行病学
J Am Soc Nephrol. 1999 Jul;10(7):1606-15. doi: 10.1681/ASN.V1071606.
7
Heart transplantation or combined heart/kidney transplantation? Even one renal biopsy may fool you.心脏移植还是心脏/肾脏联合移植?哪怕仅做一次肾活检也可能误导你。
Nephrol Dial Transplant. 1999 Apr;14(4):1014-5. doi: 10.1093/ndt/14.4.1014.

一名2型心肾综合征患者在持续非卧床腹膜透析4年后死亡,出现意外的肾脏病理检查结果。

Unforeseen renal pathological findings in a patient with type 2 cardiorenal syndrome who died after 4 years of continuous ambulatory peritoneal dialysis.

作者信息

Matsui Masaru, Okayama Satoshi, Samejima Kenichi, Saito Yoshihiko

机构信息

First Department of Internal Medicine, Nara Medical University, Nara, Japan.

出版信息

BMJ Case Rep. 2013 Jan 24;2013:bcr2012008103. doi: 10.1136/bcr-2012-008103.

DOI:10.1136/bcr-2012-008103
PMID:23354864
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3604534/
Abstract

A man in his 30s with dilated cardiomyopathy was admitted to our hospital with heart failure exacerbation. Despite optimal medical treatment, his renal function progressively declined to end-stage renal failure. Type 2 cardiorenal syndrome (CRS) was diagnosed and continuous ambulatory peritoneal dialysis was started. He died of a brainstem infarction 4 years later. Postmortem renal pathology revealed no significant changes in the glomeruli except for shrinkage, normal arterioles and focal degeneration of the tubules with peritubular fibrosis. This suggests that renal replacement therapy can be withdrawn from some patients with type 2 CRS.

摘要

一名30多岁的扩张型心肌病男性因心力衰竭加重入住我院。尽管接受了最佳药物治疗,但其肾功能仍逐渐恶化至终末期肾衰竭。诊断为2型心肾综合征(CRS),并开始持续非卧床腹膜透析。4年后,他死于脑干梗死。尸检肾脏病理显示,除肾小球萎缩外,肾小球无明显变化,小动脉正常,肾小管局灶性变性伴肾小管周围纤维化。这表明对于一些2型CRS患者可以停止肾脏替代治疗。