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铑催化的两个末端炔烃的化学和区域选择性交叉二聚反应。

Rhodium-catalyzed chemo- and regioselective cross-dimerization of two terminal alkynes.

机构信息

Shanghai Engineering Research Centre of Molecular Therapeutics and New Drug Development, East China Normal University, Shanghai, 200062, China.

出版信息

Org Lett. 2013 Feb 15;15(4):840-3. doi: 10.1021/ol303531m. Epub 2013 Jan 28.

DOI:10.1021/ol303531m
PMID:23356993
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3697770/
Abstract

Cross-dimerization of terminal arylacetylenes and terminal propargylic alcohols/amides has been achieved in the presence of a rhodium catalyst. This method features high chemo- and regioselectivities rendering convenient and atom economical access to functionalized enynes.

摘要

末端芳基乙炔和末端炔丙醇/酰胺在铑催化剂的存在下可以发生交叉二聚反应。该方法具有高化学和区域选择性，为功能化烯炔的合成提供了方便和原子经济性的方法。

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本文引用的文献

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Cobalt-catalyzed asymmetric 1,6-addition of (triisopropylsilyl)-acetylene to α,β,γ,δ-unsaturated carbonyl compounds.钴催化的（三异丙基硅基）乙炔对α，β，γ，δ-不饱和羰基化合物的不对称 1,6-加成。
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