铑催化的两个末端炔烃的化学和区域选择性交叉二聚反应。
Rhodium-catalyzed chemo- and regioselective cross-dimerization of two terminal alkynes.
机构信息
Shanghai Engineering Research Centre of Molecular Therapeutics and New Drug Development, East China Normal University, Shanghai, 200062, China.
出版信息
Org Lett. 2013 Feb 15;15(4):840-3. doi: 10.1021/ol303531m. Epub 2013 Jan 28.
Abstract
Cross-dimerization of terminal arylacetylenes and terminal propargylic alcohols/amides has been achieved in the presence of a rhodium catalyst. This method features high chemo- and regioselectivities rendering convenient and atom economical access to functionalized enynes.
摘要
末端芳基乙炔和末端炔丙醇/酰胺在铑催化剂的存在下可以发生交叉二聚反应。该方法具有高化学和区域选择性，为功能化烯炔的合成提供了方便和原子经济性的方法。
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