哥伦比亚新生儿病房中产 NDM-1 型肺炎克雷伯菌的爆发。
Outbreak of NDM-1-producing Klebsiella pneumoniae in a neonatal unit in Colombia.
机构信息
Bacterial Molecular Genetics Laboratory, Universidad El Bosque, Bogotá, Colombia.
出版信息
Antimicrob Agents Chemother. 2013 Apr;57(4):1957-60. doi: 10.1128/AAC.01447-12. Epub 2013 Jan 28.
Abstract
Six multiresistant, NDM-1-producing Klebsiella pneumoniae strains were recovered from an outbreak that affected six neonatal patients in a Colombian hospital. Molecular analysis showed that all of the isolates harbored the blaNDM-1, qnrA, and intI1 genes and were clonally related. Multilocus sequence typing showed that the isolates belonged to a new sequence type (ST1043) that was different from the sequence types that had previously been reported. This is the first report of NDM-1-producing isolates in South America.
摘要
六株多药耐药、产 NDM-1 的肺炎克雷伯菌从哥伦比亚一家医院发生的一起暴发疫情中分离得到，该疫情影响了 6 名新生儿患者。分子分析表明，所有分离株均携带 blaNDM-1、qnrA 和 intI1 基因，且具有克隆相关性。多位点序列分型显示，这些分离株属于一种新的序列型（ST1043），与先前报道的序列型不同。这是南美首次报告产 NDM-1 的分离株。
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