Department of Biology, North Carolina A&T State University, Greensboro, North Carolina 27411, USA.
J Public Health Manag Pract. 2013 Mar-Apr;19(2):110-8. doi: 10.1097/PHH.0b013e31825717ef.
To elucidate factors that influence African American willingness to participate in health-related research studies.
The African American Alzheimer disease research study group at North Carolina A&T State University designed an in-person questionnaire and surveyed more than 700 African American adults on their willingness to participate in health-related research studies. The questionnaire was distributed and collected in a nonclinical setting during the years 2008 and 2009. This study was approved by the North Carolina A&T State University Institutional Review Board.
Of the 733 valid respondents, 16% had previously participated in a health-related research study. Of these, more than 90% were willing to participate again in future research studies. Of the 614 who had never participated in a research study, more than 70% expressed willingness to participate. The majority (75%) of experienced research study participants (RSP) were older than 40 years compared with 45% of non-research study participants. Experienced research participants were also twice as likely to have a college degree compared with non-research study participants. Seventy-three percent of non-research study participants were willing to participate in research studies in the future. The factors that were probable impediments to participation included lack of time and trust. Men with knowledge of the Tuskegee Syphilis Study were 50% less likely to be willing to participate compared with those who had not heard of Tuskegee Syphilis Study.
African Americans are willing to participate in health-related research studies. Several factors such as the appropriate incentives, community trust building, outreach, and community partnership creation are necessary for engaging minority participants. Incorporating factors that target African American enrollment in research design and implementation, such as increased training of minority health ambassadors and African American researchers and public health specialists, are needed to better engage minorities across generations, in research.
阐明影响非裔美国人参与健康相关研究意愿的因素。
北卡罗来纳州农工州立大学的非裔美国人阿尔茨海默病研究小组设计了一份面对面问卷，并对 700 多名非裔美国成年人进行了调查，了解他们参与健康相关研究的意愿。该问卷于 2008 年至 2009 年期间在非临床环境中进行了分发和收集。本研究已获得北卡罗来纳州农工州立大学机构审查委员会的批准。
在 733 份有效答卷中，16%的人曾参与过健康相关的研究。其中，超过 90%的人愿意在未来的研究中再次参与。在从未参加过研究的 614 人中，超过 70%的人表示愿意参加。与非研究参与者相比，有经验的研究参与者（RSP）中超过 75%的人年龄在 40 岁以上，而 45%的非研究参与者年龄在 40 岁以上。有经验的研究参与者获得大学学位的可能性也高出两倍。73%的非研究参与者表示愿意在未来参与研究。可能阻碍参与的因素包括缺乏时间和信任。与未听说过塔斯基吉梅毒研究的人相比，对塔斯基吉梅毒研究有所了解的男性参与研究的意愿降低了 50%。
非裔美国人愿意参与健康相关的研究。需要适当的激励措施、社区信任建设、外展和社区伙伴关系建立等因素来吸引少数民族参与者。需要将针对非裔美国人入组的因素纳入研究设计和实施中，例如增加少数民族健康大使和非裔美国研究人员和公共卫生专家的培训，以更好地吸引各代少数民族参与研究。
