Lima Marina Guimarães, Santos Rejane Ferreira Reis dos, Barbosa Guilherme José Antonini, Ribeiro Guilherme de Sousa
Departamento de Farmácia Social, Faculdade de Farmácia, Universidade Federal de Minas Gerais, Belo Horizonte, Brazil.
Cien Saude Colet. 2013 Feb;18(2):499-506. doi: 10.1590/s1413-81232013000200021.
Congenital syphilis continues to be a public health problem in Brazil. The scope of this study is to describe the trends in the incidence of congenital syphilis in Belo Horizonte between 2001 and 2008 and determine risk factors associated with disease diagnosis. Data on cases of congenital syphilis and on the population of live births were obtained from the National Notifiable Diseases Information System (SINAN) and from the National Live Birth Information System (SINASC), respectively. Multivariate logistic regression analysis used the population of live births as the reference group to identify independent risk factors for congenital syphilis. The annual incidence of congenital syphilis revealed a rising trend from 0.9 to 1.6 cases per 1,000 live births between 2001 and 2008. Independent risk factors for congenital syphilis included: maternal schooling <8 years (OR: 1,3; 95% CI: 1,2-1,4); black or mixed maternal race (2,1; 1,5-2,8) and lack of antenatal care (11,4; 8,5-15,4). The strong association between the lack of antenatal care and congenital syphilis indicates that universalization of antenatal care is critical for the control of congenital syphilis. The effective control of the disease in Brazil will depend on actions to reduce social inequities in health.
先天性梅毒在巴西仍是一个公共卫生问题。本研究旨在描述2001年至2008年贝洛奥里藏特市先天性梅毒的发病趋势,并确定与疾病诊断相关的危险因素。先天性梅毒病例数据和活产人口数据分别取自国家法定传染病信息系统(SINAN)和国家活产信息系统(SINASC)。多变量逻辑回归分析以活产人口作为参照组,以确定先天性梅毒的独立危险因素。2001年至2008年,先天性梅毒的年发病率呈上升趋势,从每1000例活产0.9例升至1.6例。先天性梅毒的独立危险因素包括:母亲受教育年限<8年(比值比:1.3;95%置信区间:1.2 - 1.4);母亲为黑人或混血人种(2.1;1.5 - 2.8)以及缺乏产前护理(11.4;8.5 - 15.4)。缺乏产前护理与先天性梅毒之间的强烈关联表明,普及产前护理对控制先天性梅毒至关重要。巴西对该疾病的有效控制将取决于减少健康方面社会不平等的行动。