Cimolin Veronica, Galli Manuela, Rigoldi Chiara, Grugni Graziano, Vismara Luca, de Souza Shirley Aparecida Fabris, Mainardi Luca, Albertini Giorgio, Capodaglio Paolo
a Dipartimento di Elettronica , Informazione e Bioingegneria , Politecnico di Milano , Italy.
Comput Methods Biomech Biomed Engin. 2014;17(14):1535-41. doi: 10.1080/10255842.2012.753068. Epub 2013 Jan 29.
The suitability of new dynamic system analysis was investigated to compare postural control in Prader-Willi syndrome (PWS) and Down syndrome (DS) patients. Time-domain, frequency-domain parameters and fractal dimension (FD) of centre of pressure (CoP) were computed in maintaining normal standing on a force platform in 20 DS and 13 PWS patients, compared to 26 obese (obese control group, OCG) and 20 healthy individuals (healthy control group, HCG). DS and PWS showed greater displacements along both directions and longer sway path (SP) parameter than HCG and OCG, with statistical differences between PWS and DS for anteroposterior displacement and SP. DS used higher frequency strategy when compared to PWS, OCG and HCG. Both DS and PWS were characterised by greater values of FD than OCG and HCG, with higher values in DS. The analyses in frequency domain and of the dynamic nature of CoP suggest that DS patients are characterised by a more complex and irregular signal than PWS patients.
研究了新的动态系统分析方法，以比较普拉德-威利综合征（PWS）和唐氏综合征（DS）患者的姿势控制。在20名DS患者、13名PWS患者、26名肥胖者（肥胖对照组，OCG）和20名健康个体（健康对照组，HCG）在测力平台上保持正常站立时，计算了压力中心（CoP）的时域、频域参数和分形维数（FD）。与HCG和OCG相比，DS和PWS在两个方向上的位移更大，摆动路径（SP）参数更长，PWS和DS在前后位移和SP方面存在统计学差异。与PWS、OCG和HCG相比，DS采用更高频率的策略。DS和PWS的FD值均高于OCG和HCG，DS的值更高。频域分析和CoP的动态特性表明，DS患者的信号比PWS患者更复杂、更不规则。
