《荷兰轮状病毒疫苗接种的成本效益：共识轮状病毒疫苗模型的结果更新》
An update of "Cost-effectiveness of rotavirus vaccination in the Netherlands: the results of a Consensus Rotavirus Vaccine model".
机构信息
Institute of Health Policy, Management and Evaluation, University of Toronto, Ontario, Canada.
出版信息
BMC Infect Dis. 2013 Jan 30;13:54. doi: 10.1186/1471-2334-13-54.
Abstract
BACKGROUND
To update a cost-effectiveness analysis of rotavirus vaccination in the Netherlands previously published in 2011.
METHODS
The rotavirus burden of disease and the indirect protection of older children and young adults (herd protection) were updated.
RESULTS
When updated data was used, routine infant rotavirus vaccination in the Netherlands would potentially become an even more cost-effective strategy than previously estimated with the incremental cost per QALY at only €3,000-4,000. Break-even total vaccination costs were indicated at €92-122, depending on the applied threshold.
CONCLUSIONS
We concluded that the results on potentially favourable cost-effectiveness in the previous study remained valid, however, the new data suggested that previous results might represent an underestimation of the economic attractiveness of rotavirus vaccination.
摘要
背景
更新先前于 2011 年发表的荷兰轮状病毒疫苗接种的成本效益分析。
方法
更新了轮状病毒疾病负担和对年龄较大的儿童和年轻人（群体保护）的间接保护。
结果
当使用更新的数据时，荷兰常规婴儿轮状病毒疫苗接种可能比之前估计的更具成本效益，每增加一个质量调整生命年的增量成本仅为 3000-4000 欧元。根据应用的阈值，盈亏平衡的总疫苗接种成本为 92-122 欧元。
结论
我们得出的结论是，先前研究中关于潜在有利的成本效益的结果仍然有效，但是新数据表明，先前的结果可能低估了轮状病毒疫苗接种的经济吸引力。
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