Department of Nutrition, The University of North Carolina, Chapel Hill, NC, USA.
Am J Clin Nutr. 2013 Mar;97(3):604-11. doi: 10.3945/ajcn.112.048405. Epub 2013 Jan 30.
Little is understood about the effect of increased consumption of low-calorie sweeteners in diet beverages on dietary patterns and energy intake.
We investigated whether energy intakes and dietary patterns were different in subjects who were randomly assigned to substitute caloric beverages with either water or diet beverages (DBs).
Participants from the Choose Healthy Options Consciously Everyday randomized clinical trial (a 6-mo, 3-arm study) were included in the analysis [water groups: n = 106 (94% women); DB group: n = 104 (82% women)]. For energy, macronutrient, and food and beverage intakes, we investigated the main effects of time, treatment, and the treatment-by-time interaction by using mixed models.
Overall, the macronutrient composition changed in both groups without significant differences between groups over time. Both groups reduced absolute intakes of total daily energy, carbohydrates, fat, protein, saturated fat, total sugar, added sugar, and other carbohydrates. The DB group decreased energy from all beverages more than the water group did only at month 3 (P-group-by-time < 0.05). Although the water group had a greater reduction in grain intake at month 3 and a greater increase in fruit and vegetable intake at month 6 (P-group-by-time < 0.05), the DB group had a greater reduction in dessert intake than the water group did at month 6 (P-group-by-time < 0.05).
Participants in both intervention groups showed positive changes in energy intakes and dietary patterns. The DB group showed decreases in most caloric beverages and specifically reduced more desserts than the water group did. Our study does not provide evidence to suggest that a short-term consumption of DBs, compared with water, increases preferences for sweet foods and beverages. This trial was registered at clinicaltrials.gov as NCT01017783.
人们对在饮食中增加低热量甜味剂的摄入量对饮食模式和能量摄入的影响知之甚少。
我们研究了随机分配饮用白开水或低糖饮料(DB)替代含糖饮料的受试者的能量摄入和饮食模式是否存在差异。
本研究纳入了“有意识地每天选择健康饮食”(CHOICE)随机临床试验(为期 6 个月,分为 3 组)的参与者[白开水组:n = 106(94%为女性);DB 组:n = 104(82%为女性)]。我们通过混合模型研究了时间、处理方式以及处理方式与时间的交互作用对能量、宏量营养素以及食物和饮料摄入的主要影响。
总体而言,两组的宏量营养素组成均发生了变化,但两组之间在时间上无显著差异。两组均减少了总日能量、碳水化合物、脂肪、蛋白质、饱和脂肪、总糖、添加糖和其他碳水化合物的绝对摄入量。仅在第 3 个月时,DB 组较白开水组从所有饮料中摄入的能量减少更多(P-组间时间 < 0.05)。尽管白开水组在第 3 个月时谷物摄入量减少更多,而第 6 个月时水果和蔬菜摄入量增加更多(P-组间时间 < 0.05),但 DB 组在第 6 个月时甜点摄入量的减少量大于白开水组(P-组间时间 < 0.05)。
两组干预组的参与者的能量摄入和饮食模式均出现积极变化。DB 组减少了大部分含热量饮料的摄入,尤其是减少了比白开水组更多的甜点摄入量。本研究并未提供短期摄入 DB 会增加对甜食和饮料偏好的证据。本试验在 clinicaltrials.gov 上注册,编号为 NCT01017783。