Nothern Ontario School of Medicine, Sudbury, Ontario, Canada.
J Cutan Med Surg. 2013 Jan-Feb;17(1):66-8. doi: 10.2310/7750.2012.12015.
Yellow nail syndrome (YNS) is a rare clinical entity of unknown etiology that is characterized by a triad of yellow nails, respiratory manifestations, and lymphedema. The condition appears in the mid- to later years of life and only rarely in childhood. We describe a rare case of YNS with an atypical clinical presentation consisting of only yellow and dystrophic nails in a 2-year-old female since birth.
A case of congenital YNS with only dystrophic and yellow nails is reported.
A 2-year-old female presented with yellow nails since birth. There was no positive family history. Physical examination revealed 20 thickened, dystrophic, yellow nails with onycholysis. There was no evidence of respiratory manifestations or lymphedema.
Although rare, YNS can present as a congenital clinical entity and persist after birth. Pediatric patients with YNS show different clinical manifestations than the classic adult patient. The presence of yellow and dystrophic nails in the absence of respiratory and lymphatic manifestations may be the only sign of pathology and warrants close monitoring as progression to more serious complications can occur.
黄甲综合征（YNS）是一种病因不明的罕见临床病症，其特征为三联征，包括黄色指甲、呼吸系统表现和淋巴水肿。该病症出现在中年以后，很少在儿童期出现。我们描述了一例罕见的 YNS 病例，其临床表现不典型，仅为一名 2 岁女性自出生以来就存在的黄色和营养不良指甲。
报告一例仅表现为营养不良和黄色指甲的先天性 YNS。
一名 2 岁女性自出生以来就存在黄色指甲。无阳性家族史。体格检查显示 20 个增厚、营养不良、黄色指甲伴甲分离。无呼吸系统表现或淋巴水肿。
尽管罕见，YNS 也可以表现为先天性临床病症，并在出生后持续存在。YNS 的儿科患者与经典的成年患者表现出不同的临床表现。在没有呼吸系统和淋巴系统表现的情况下出现黄色和营养不良指甲可能是唯一的病理征象，需要密切监测，因为可能会出现更严重的并发症。
