State Key Laboratory of Organometallic Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, 345 Lingling Lu, Shanghai 200032, China.
Org Biomol Chem. 2013 Feb 13;11(10):1602-5. doi: 10.1039/c3ob00072a.
Chiral phosphoric acid works together with Hoveyda-Grubbs II catalyst enabling highly efficient synthesis of enantioenriched tetrahydro-β-carboline (up to 95% yield, 90% ee) through an olefin isomerization/Pictet-Spengler cascade reaction via sequential catalysis.
手性磷酸与 Hoveyda-Grubbs II 催化剂协同作用，通过烯烃异构化/Pictet-Spengler 级联反应的顺序催化，实现了高效合成手性富集的四氢-β-咔啉（高达 95%的产率，90%的对映选择性）。
