Borisov Iu Iu
Ter Arkh. 1990;62(2):43-5.
As many as 57 patients with ulcer disease and 14 normal persons were examined for rheological properties of gastric mucus and gastric secretion in the basal period and in response to maximum stimulation with pentagastrin. It has been established that in patients with ulcer disease, elastic and viscous properties of parietal gastric mucus are decreased, with the intensity and the rate of rheological derangements being dependent on ulcer site. Changes in the rheological parameters of mucus are not related to pathological deviations in gastric secretion of acid and pepsin, occurring much more frequently than the latter ones. This fact points to the independent pathogenetic and diagnostic importance of the above changes.
对多达57例溃疡病患者和14名正常人在基础期以及用五肽胃泌素进行最大刺激后的胃黏液和胃分泌的流变学特性进行了检测。已经确定，溃疡病患者胃壁黏液的弹性和黏性特性降低，流变学紊乱的强度和速率取决于溃疡部位。黏液流变学参数的变化与胃酸和胃蛋白酶分泌的病理偏差无关，前者比后者更频繁地出现。这一事实表明上述变化具有独立的致病和诊断意义。
