胃黏液黏度与消化性溃疡
Gastric mucus viscosity and peptic ulcer.
作者信息
Pringle R
出版信息
Adv Exp Med Biol. 1977;89:227-37. doi: 10.1007/978-1-4613-4172-7_17.
PMID:930722
Abstract
The following observations have been made: 1. The viscosity of a substance as complex as mucus requires study at different rates of shear and shear stresses. 2. Visible gastric mucus behaves as a pseudoplastic substance. 3. Duodenal ulcer patients have a higher gastric mucus viscosity than controls. 4. Pentagastrin stimulation in duodenal ulcer patients leads to the secretion of gastric mucus of low viscosity. 5. This decrease in the viscosity of gastric mucus on pentagastrin stimulation does not occur in patients with gastric ulcer. 6. Truncal vagotomy leads to an increase in the viscosity of gastric mucus under basal and stimulted conditions.
摘要
已得出以下观察结果
- 像黏液这样复杂的物质的黏度需要在不同的剪切速率和剪应力下进行研究。2. 可见的胃黏液表现为假塑性物质。3. 十二指肠溃疡患者的胃黏液黏度高于对照组。4. 十二指肠溃疡患者接受五肽胃泌素刺激会导致低黏度胃黏液的分泌。5. 胃溃疡患者在五肽胃泌素刺激下不会出现胃黏液黏度的这种降低。6. 迷走神经干切断术会导致基础状态和刺激状态下胃黏液黏度增加。
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