Sakai Koji, Sakamoto Ryo, Okada Tomohisa, Sugimoto Naozo, Togashi Kaori
Department of Human Health Science, Graduate School of Medicine, Kyoto University, Kyoto, Japan.
Annu Int Conf IEEE Eng Med Biol Soc. 2012;2012:2291-3. doi: 10.1109/EMBC.2012.6346420.
Among MR methods, the most clinically applicable temperature measurement method at deep brain might be the diffusion-weighted image (DWI) thermometry. Although only applicable to cerebrospinal fluid (CSF), it is thought to be potentially useful in assessing the thermal pathophysiology of the brain in both patients and healthy subjects. The purpose of this study was to investigate the effects of b-value, pixel resolution, magnet strength and signal to noise ratio (SNR) for the DWI-thermometry with healthy volunteer. Formerly, an ADC from b=0 and b=1000 has been thought to be useful for diffusion thermometry, this study revealed b=200 to 800 was more appropriate for DWI thermometry. The SNR was strongly affected the results of DWI thermometry.
在磁共振成像（MR）方法中，深部脑区最具临床应用价值的温度测量方法可能是扩散加权成像（DWI）测温法。尽管它仅适用于脑脊液（CSF），但人们认为它在评估患者和健康受试者的脑部热病理生理学方面可能具有潜在用途。本研究的目的是探讨b值、像素分辨率、磁场强度和信噪比（SNR）对健康志愿者进行DWI测温的影响。以前，人们认为b = 0和b = 1000时的表观扩散系数（ADC）对扩散测温有用，但本研究表明b = 200至800更适合DWI测温。信噪比强烈影响DWI测温结果。
