一种整合癌症模型存储库的架构。

An architecture for integrating cancer model repositories.

作者信息

Sfakianakis Stelios, Sakkalis Vangelis, Marias Kostas, Stamatakos Georgios, McKeever Steve, Deisboeck Thomas S, Graf Norbert

机构信息

Institute of Computer Science at FORTH, Vassilika Vouton, GR-70013 Heraklion, Crete, Greece.

出版信息

Annu Int Conf IEEE Eng Med Biol Soc. 2012;2012:6628-31. doi: 10.1109/EMBC.2012.6347514.

DOI:10.1109/EMBC.2012.6347514

PMID:23367449

Abstract

The TUMOR project aims at developing a European clinically oriented semantic-layered cancer digital model repository from existing EU projects that will be interoperable with the US grid-enabled semantic-layered digital model repository platform at CViT.org (Center for the Development of a Virtual Tumor, Massachusetts General Hospital (MGH), Boston, USA) which is NIH/NCI-caGRID compatible. In this paper we describe the modular and federated architecture of TUMOR that effectively addresses model integration, interoperability, and security related issues.

摘要

肿瘤项目旨在从现有的欧盟项目中开发一个面向临床的欧洲语义分层癌症数字模型存储库，该存储库将与美国CViT.org（虚拟肿瘤开发中心，美国马萨诸塞州波士顿市麻省总医院）的支持网格的语义分层数字模型存储库平台实现互操作，该平台与美国国立卫生研究院/国家癌症研究所的caGRID兼容。在本文中，我们描述了肿瘤项目的模块化和联合架构，该架构有效地解决了与模型集成、互操作性和安全性相关的问题。