Orthopedic Surgery, Keio University School of Medicine, Shinjuku, Tokyo, Japan.
J Neurosurg Spine. 2013 Apr;18(4):321-6. doi: 10.3171/2013.1.SPINE12426. Epub 2013 Feb 1.
The authors undertook this study to evaluate curve progression, risk factors for curve progression, and outcomes after decompression surgery in patients with degenerative lumbar scoliosis with minimal to moderate curvature.
Of 852 patients with lumbar canal stenosis treated by posterior decompression surgery, 50 patients had a lumbar curve greater than 10° at final follow-up. These patients were divided into 2 groups according to curve progression during the follow-up period: the P group (11 patients), with a curve progression of more than 5°, and the NP group (39 patients), with a curve progression of 5° or less. The authors compared preoperative parameters in these 2 groups to elucidate risk factors associated with curve progression and other surgical outcomes.
The average lumbar curve progression in the total group of 50 patients was 3.4° ± 3.9° (range -2.0° to 22.0°). In the P group the average curve progression was 8.5°, and in the NP group it was 2.0°. Multivariate logistic regression analysis showed no significant association between curve progression and any of the potential risk factors evaluated (including curve magnitude, decompression method, and degenerative intervertebral disc changes). Spur formation, evaluated with the Nathan classification at the concave side of the curve, tended to be greater in the P group, although the difference was not statistically significant. There was no significant difference in revision surgery rate, and none of the patients required arthrodesis due to curve progression. Clinical outcomes, evaluated with the Japanese Orthopaedic Association Back Pain Evaluation Questionnaire and the Scoliosis Research Society 22-question questionnaire, were also similar in the 2 groups.
Surgical outcomes did not deteriorate in the P group. While curve progression after decompression surgery could not be predicted from the preoperative factors considered, spur formation at the concave side of the curve may be a candidate factor. The results of this study indicate that spinal fixation to halt deformity progression is not always necessary if the patient's pathological condition derives mainly from canal stenosis.
本研究旨在评估退行性腰椎侧凸患者中,接受减压手术后,曲度进展的情况、进展的危险因素以及结果。
在接受后路减压手术治疗的 852 例腰椎管狭窄症患者中,有 50 例患者最终随访时腰椎曲线大于 10°。根据随访期间的曲线进展情况,将这些患者分为两组:P 组(11 例),曲线进展超过 5°;NP 组(39 例),曲线进展为 5°或以下。作者比较了这两组患者的术前参数,以阐明与曲线进展和其他手术结果相关的危险因素。
50 例患者的总平均腰椎曲线进展为 3.4°±3.9°(范围-2.0°至 22.0°)。P 组的平均曲线进展为 8.5°,NP 组为 2.0°。多变量逻辑回归分析显示,曲线进展与评估的任何潜在危险因素之间均无显著相关性(包括曲线幅度、减压方法和退行性椎间盘变化)。在曲线凹侧,根据 Nathan 分类评估的骨刺形成在 P 组中往往更大,但差异无统计学意义。翻修手术率无显著差异,也没有因曲线进展而需要融合的患者。在两组中,日本矫形协会腰痛评估问卷和脊柱侧凸研究协会 22 项问卷评估的临床结果也相似。
P 组的手术结果并未恶化。虽然无法根据术前考虑的因素预测减压手术后的曲线进展,但曲线凹侧的骨刺形成可能是一个候选因素。本研究结果表明,如果患者的病理状况主要源于椎管狭窄,那么不一定需要脊柱固定来阻止畸形进展。