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经皮椎间孔内镜减压治疗老年退行性腰椎侧凸伴椎管狭窄的临床疗效:一项匹配对照研究。

Clinical outcomes of percutaneous transforaminal endoscopic decompression for the treatment of degenerative lumbar scoliosis associated with spinal stenosis in elderly individuals: a matched comparison study.

机构信息

Department of Orthopedics, Beijing Chaoyang Hospital, Capital Medical University, 5 JingYuan Road, Shijingshan District, Beijing, 100043, China.

出版信息

Int Orthop. 2024 Dec;48(12):3197-3205. doi: 10.1007/s00264-024-06318-x. Epub 2024 Sep 25.

DOI:10.1007/s00264-024-06318-x
PMID:39320498
Abstract

PURPOSE

This retrospective cohort study evaluated the efficacy and safety of percutaneous transforaminal endoscopic decompression (PTED) in elderly patients with degenerative lumbar scoliosis (DLS) associated with lumbar spinal stenosis (LSS).

STUDY DESIGN

A matched comparison study.

METHODS

In total, 97 patients with DLS associated with LSS who underwent PTED under local anesthesia between 2016 and 2021 were retrospectively analyzed. Using the inclusion and exclusion criteria, 24 patients aged ≥ 80 years were screened and included in the study group. Then, 24 patients aged 50-80 years were matched according to gender, date of surgery, and surgical levels were included in the control group. Clinical outcomes such as the visual analog scale (VAS) score, Oswestry Disability Index (ODI) score, modified MacNab criteria, radiological parameters, and complications were assessed. The independent sample t-test, Pearson's chi-square test and Fisher's exact test were used to compare the parameters between the study and control groups.

RESULTS

The study group had significantly higher mean American Society of Anesthesiologists classification and age-adjusted Charlson Comorbidity Index scores than the control group (2.42 ± 0.72) vs. 5.25 ± 1.03 and 1.67 ± 0.76 vs. 3.17 ± 2.10, respectively). The VAS scores for pain in two legs and back and ODI scores significantly improved at two weeks after surgery and at the final followup (p < 0.05). The study group had higher back pain VAS and ODI scores than the control group at the final followup (p < 0.05). In addition, the complication and patient satisfaction rates were similar between the two groups (p > 0.05). The overall radiological parameters were comparable between the two groups, and there was no significant deterioration in coronal imbalance or loss of disc height between the two groups.

CONCLUSION

Elderly patients (aged ≥ 80 years) with DLS associated with LSS are less fit and have a greater number of comorbidities. However, they can achieve satisfactory outcomes with PTED, which are comparable to those of patients < 80 years. PTED under local anesthesia can also be an efficient alternative to conventional open lumbar decompression surgery for treating elderly patients with comorbidities.

摘要

目的

本回顾性队列研究评估了经皮椎间孔内镜减压术(PTED)治疗伴有腰椎管狭窄症(LSS)的退行性腰椎侧凸(DLS)老年患者的疗效和安全性。

研究设计

匹配对照研究。

方法

共回顾性分析了 2016 年至 2021 年间在局部麻醉下接受 PTED 治疗的 97 例 DLS 合并 LSS 患者。根据纳入和排除标准,筛选出 24 例年龄≥80 岁的患者作为研究组,然后按照性别、手术日期和手术节段,匹配年龄 50-80 岁的 24 例患者作为对照组。评估了视觉模拟评分(VAS)、Oswestry 功能障碍指数(ODI)、改良 MacNab 标准、影像学参数和并发症等临床结果。采用独立样本 t 检验、Pearson χ²检验和 Fisher 确切检验比较研究组和对照组的参数。

结果

研究组的美国麻醉医师协会分级和年龄调整 Charlson 合并症指数评分均明显高于对照组(2.42±0.72)比(5.25±1.03)和(1.67±0.76)比(3.17±2.10)。术后 2 周和末次随访时,两组腿痛和腰痛的 VAS 评分及 ODI 评分均明显改善(p<0.05)。末次随访时,研究组的腰痛 VAS 评分和 ODI 评分均高于对照组(p<0.05)。此外,两组的并发症发生率和患者满意度无差异(p>0.05)。两组的总体影像学参数相似,两组间冠状面失衡或椎间盘高度丢失无明显恶化。

结论

伴有 LSS 的 DLS 老年患者(年龄≥80 岁)身体状况较差,合并症较多。然而,他们通过 PTED 可获得满意的结果,与<80 岁的患者相当。局部麻醉下的 PTED 也可以作为治疗伴有合并症的老年患者的一种有效的替代传统开放式腰椎减压手术的方法。

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