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[4-甲基尿嘧啶和肌肽对大鼠皮肤伤口愈合的影响]

[Effects of 4-methyluracil and carnosine on healing of skin wounds in rats].

作者信息

Silaeva S A, Guliaeva N V, Khatsernova B Ia, Onufriev M V, Nikolaev A Ia

出版信息

Biull Eksp Biol Med. 1990 Feb;109(2):180-2.

PMID:2337657
Abstract

In experiments in vivo and in vitro the authors studied antioxidative properties of 4-methyluracil and carnosine, their capacity to inhibit sex and accelerate healing of skin wounds. 4-methyluracil and carnosine discover almost the same capacity to decrease in the tissues of the wound and the blood serum in the formation of various intermediate products of free radical oxidation. Data are given on the study of the dynamics of wound healing after a 5-day treatment with equimolar quantities.

摘要

在体内和体外实验中,作者研究了4-甲基尿嘧啶和肌肽的抗氧化特性、它们抑制炎症和加速皮肤伤口愈合的能力。4-甲基尿嘧啶和肌肽在伤口组织和血清中自由基氧化各种中间产物形成过程中,降低自由基的能力几乎相同。文中给出了用等摩尔量进行5天治疗后伤口愈合动态的研究数据。

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