El-Masry S, Wahbi A A
J Assoc Off Anal Chem. 1978 Jan;61(1):65-7.
A rapid method is presented for determining strychnine and brucine in liquid galenicals. At pH 5.0, both strychnine and brucine are complexed with methyl orange. After treatment with 0.1N NaOH, the liberated alkaloids are determined spectrophotometrically, using the 2-wavelength method of analysis. The method has been successfully applied to the analysis of 4 batches of nux vomica tincture, nux vomica acid, and nux vomica alkaline mixtures. The method has a relative standard deviation of 0.52%.
本文介绍了一种快速测定液体制剂中士的宁和马钱子碱的方法。在pH 5.0条件下，士的宁和马钱子碱均与甲基橙络合。用0.1N氢氧化钠处理后，采用双波长分光光度法测定游离生物碱。该方法已成功应用于4批马钱子酊、马钱子酸和马钱子碱混合物的分析。该方法的相对标准偏差为0.52%。
