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高危椎间盘切除术患者:使用环形封闭装置预防大环形缺损患者的再突出。

The high-risk discectomy patient: prevention of reherniation in patients with large anular defects using an anular closure device.

机构信息

Department of Neurosurgery, Academic Medical Center, St. Lucas-Andreas Ziekenhuis, Jan Tooropstaat 164, 1061 AE, Amsterdam, The Netherlands.

出版信息

Eur Spine J. 2013 May;22(5):1030-6. doi: 10.1007/s00586-013-2656-1. Epub 2013 Feb 3.

Abstract

PURPOSE

With lumbar discectomy for disc herniation, surgeons must choose between limited nucleus removal associated with higher reherniation risk or more aggressive nucleus removal associated with increased back pain and disc degeneration. This trade-off is particularly challenging in patients with large anular defects, which carry the highest risk of reherniation. We examined the effect of an anular closure device on reherniation and clinical outcomes.

METHODS

Seventy-five primary discectomy patients had a limited discectomy followed by implantation of an anular closure device and were followed-up to 2 years. Anular defect size and volume of removed nucleus was recorded at surgery. Reherniations were reported, pain and function were monitored throughout, and imaging was performed at annual visits.

RESULTS

The overall symptomatic reherniation rate was 1.4%, and the asymptomatic reherniation rate was 1.5% at 12 months and 5.1% at 24 months. Both rates compare favorably with literature reports which include symptomatic rates ranging between 2 and 18% (up to 27% for patients with large anular defects) and an asymptomatic rate of 13%.

CONCLUSIONS

The low reherniation rate in patients at high-risk of reherniation based on anular defect size, despite discectomy being only limited, suggests that an anular closure device may reduce reherniation risk. Clinical outcomes for pain and function at 1 and 2 years post-operatively compared favorably with literature reports. Further study in a randomized controlled trial is required to confirm these results.

摘要

目的

对于椎间盘突出症的腰椎间盘切除术,外科医生必须在与较高复发风险相关的有限核切除与与增加的背痛和椎间盘退变相关的更激进的核切除之间做出选择。在具有较大环状缺陷的患者中,这种权衡尤其具有挑战性,因为它们具有最高的复发风险。我们研究了环状闭合装置对复发和临床结果的影响。

方法

75 例原发性椎间盘切除术患者进行了有限的椎间盘切除术,然后植入环状闭合装置,并随访至 2 年。在手术中记录了环状缺陷的大小和切除的核体积。报告了复发情况,在整个过程中监测了疼痛和功能,并在每年的就诊时进行了影像学检查。

结果

总的症状性复发率为 1.4%,12 个月时无症状性复发率为 1.5%,24 个月时无症状性复发率为 5.1%。这两个比率与文献报告中的比率相比都有利,文献报告中的比率包括症状性复发率在 2%至 18%之间(对于具有较大环状缺陷的患者,最高可达 27%),无症状性复发率为 13%。

结论

尽管椎间盘切除术仅为有限切除,但基于环状缺陷大小,在具有高复发风险的患者中复发率较低,这表明环状闭合装置可能降低复发风险。术后 1 年和 2 年的疼痛和功能临床结果与文献报告相比有利。需要进一步的随机对照试验来证实这些结果。

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