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腰椎间盘切除术后纤维环闭合对椎间盘高度维持及再手术复发性疝的影响:两年数据

Effect of anular closure on disk height maintenance and reoperated recurrent herniation following lumbar diskectomy: two-year data.

作者信息

Ledic Darko, Vukas Duje, Grahovac Gordan, Barth Martin, Bouma Gerrit J, Vilendecic Milorad

机构信息

Department of Neurosurgery, University Hospital Center of Rijeka, Rijeka, Croatia.

Department of Neurosurgery, Clinical Hospital Dubrava, Zagreb, Croatia.

出版信息

J Neurol Surg A Cent Eur Neurosurg. 2015 May;76(3):211-8. doi: 10.1055/s-0034-1393930. Epub 2015 Jan 14.

Abstract

OBJECTIVE

To assess the potential benefits of disk reherniation reduction and disk height maintenance in limited diskectomy combined with the implantation of the anular closure device.

SUMMARY AND BACKGROUND DATA

Postoperative disk height loss is apparent in most patients undergoing lumbar diskectomy for herniated nucleus pulposus. Less favorable patient outcomes are associated with significant loss in disk height that can occur after aggressive disk tissue removal. More conservative disk removals, however, are often burdened by the increased risk of recurrent disk herniation.

METHODS

Two prospective single-arm studies on patients treated with limited diskectomy and an anular closure device were conducted. Outcome measures included disk height maintenance relative to preoperative values, Oswestry Disability Index, back pain, leg pain, and complications such as reherniations. Patients were evaluated preoperatively and postoperatively at 6 weeks and at 3-, 6-, 12-, and 24-month time points.

RESULTS

A total of 75 patients were included in this cohort consisting of 40 men and 35 women with an average age of 40 years. Disk height maintenance within the group overall was 90% at 24 months. Overall, 97% of the treated disks demonstrated disk height maintenance of at least 75% of preoperative levels at 12 months and 92% at 24 months. Disk height maintenance was correlated with less nucleus removal. Patient disability, back pain, and leg pain were significantly improved from preoperative levels at 6 weeks and maintained over the course of study. There was a single symptomatic reherniation requiring surgical intervention within this series.

CONCLUSIONS

Limited lumbar diskectomy combined with the use of an anular closure device provided very low rates of disk reherniation and exhibited excellent disk height maintenance and sustained disability, leg pain, and back pain improvement within a 24-month postoperative study period. As with prior diskectomy studies, disk height maintenance was correlated with lower nucleus removal, although recurrence was less than in prior reports of limited diskectomy. Anular closure may allow for achievement of both objectives.

摘要

目的

评估在有限椎间盘切除术联合植入纤维环闭合装置时,减少椎间盘再突出和维持椎间盘高度的潜在益处。

总结与背景数据

大多数接受腰椎间盘突出症椎间盘切除术的患者术后会出现椎间盘高度丢失。积极切除椎间盘组织后发生的显著椎间盘高度丢失与较差的患者预后相关。然而,更保守的椎间盘切除术往往因椎间盘再突出风险增加而受到影响。

方法

对接受有限椎间盘切除术和纤维环闭合装置治疗的患者进行了两项前瞻性单臂研究。结果指标包括相对于术前值的椎间盘高度维持情况、Oswestry功能障碍指数、背痛、腿痛以及再突出等并发症。在术前、术后6周以及术后3、6、12和24个月时间点对患者进行评估。

结果

该队列共纳入75例患者,其中男性40例,女性35例,平均年龄40岁。该组在24个月时总的椎间盘高度维持率为90%。总体而言,97%的治疗椎间盘在12个月时椎间盘高度维持至少为术前水平的75%,在24个月时为92%。椎间盘高度维持与较少的髓核切除相关。患者的功能障碍、背痛和腿痛在术后6周时较术前水平有显著改善,并在研究过程中保持。该系列中有1例有症状的再突出需要手术干预。

结论

在一项为期24个月的术后研究中,有限腰椎间盘切除术联合使用纤维环闭合装置导致椎间盘再突出率极低,显示出优异的椎间盘高度维持效果,并持续改善功能障碍、腿痛和背痛。与先前的椎间盘切除术研究一样,椎间盘高度维持与较低的髓核切除相关,尽管复发率低于先前有限椎间盘切除术的报告。纤维环闭合可能实现这两个目标。

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