Department of Medicine and Clinical Science, Okayama University Graduate School of Medicine, Dentistry, and Pharmaceutical Sciences, Okayama, Japan.
Clin Exp Nephrol. 2013 Apr;17(2):155-73. doi: 10.1007/s10157-012-0746-8. Epub 2013 Feb 6.
The Japan Renal Biopsy Registry (J-RBR) was started in 2007 and the Japan Kidney Disease Registry (J-KDR) was then started in 2009 by the Committee for Standardization of Renal Pathological Diagnosis and the Committee for the Kidney Disease Registry of the Japanese Society of Nephrology. The purpose of this report is to describe and summarize the registered data from 2009 and 2010. For the J-KDR, data were collected from 4,016 cases, including 3,336 (83.1 %) by the J-RBR and 680 (16.9 %) other cases from 59 centers in 2009, and from 4,681 cases including 4,106 J-RBR cases (87.7 %) and 575 other cases (12.3 %) from 94 centers in 2010, including the affiliate hospitals. In the J-RBR, 3,165 native kidneys (94.9 %) and 171 renal grafts (5.1 %) and 3,869 native kidneys (94.2 %) and 237 renal grafts (5.8 %) were registered in 2009 and 2010, respectively. Patients younger than 20 years of age comprised 12.1 % of the registered cases, and those 65 years and over comprised 24.5 % of the cases with native kidneys in 2009 and 2010. The most common clinical diagnosis was chronic nephritic syndrome (55.4 % and 50.0 % in 2009 and 2010, respectively), followed by nephrotic syndrome (22.4 % and 27.0 %); the most frequent pathological diagnosis as classified by the pathogenesis was IgA nephropathy (31.6 % and 30.4 %), followed by primary glomerular diseases (except IgA nephropathy) (27.2 % and 28.1 %). Among the primary glomerular diseases (except IgA nephropathy) in the patients with nephrotic syndrome, membranous nephropathy was the most common histopathology in 2009 (40.3 %) and minor glomerular abnormalities (50.0 %) were the most common in 2010 in native kidneys in the J-RBR. Five new secondary and longitudinal research studies by the J-KDR were started in 2009 and one was started in 2010.
日本肾脏病理登记研究（J-RBR）于 2007 年启动，日本肾脏疾病登记研究（J-KDR）于 2009 年由日本肾脏病学会肾脏病理诊断标准化委员会和肾脏疾病登记委员会启动。本报告旨在描述和总结 2009 年和 2010 年登记的数据。对于 J-KDR，2009 年共收集了 4016 例病例数据，其中 3336 例（83.1%）来自 J-RBR，680 例（16.9%）来自 59 个中心的其他病例；2010 年共收集了 4681 例病例数据，其中 4106 例（87.7%）来自 J-RBR，575 例（12.3%）来自 94 个中心的其他病例（包括附属医院）。在 J-RBR 中，2009 年和 2010 年分别登记了 3165 例固有肾脏（94.9%）和 171 例移植肾脏（5.1%），以及 3869 例固有肾脏（94.2%）和 237 例移植肾脏（5.8%）。2009 年和 2010 年登记的病例中，年龄小于 20 岁的患者占 12.1%，年龄在 65 岁及以上的患者中，固有肾脏的占比分别为 24.5%。最常见的临床诊断是慢性肾炎综合征（2009 年和 2010 年分别为 55.4%和 50.0%），其次是肾病综合征（22.4%和 27.0%）；按发病机制分类，最常见的病理诊断是 IgA 肾病（31.6%和 30.4%），其次是原发性肾小球疾病（除 IgA 肾病外）（27.2%和 28.1%）。在肾病综合征患者的原发性肾小球疾病（除 IgA 肾病外）中，2009 年膜性肾病是最常见的组织病理学类型（40.3%），2010 年固有肾脏中最常见的是微小肾小球异常（50.0%）。J-KDR 于 2009 年启动了 5 项新的二级和纵向研究，2010 年启动了 1 项。
