Department of Psychology, Wayne State University, Detroit, MI 48202, USA.
Clin Neuropsychol. 2013;27(3):356-75. doi: 10.1080/13854046.2013.765507. Epub 2013 Feb 8.
This study evaluated the incremental utility of neuropsychological tests to computed tomography (CT) in predicting long-term outcomes of adults with moderate to severe traumatic brain injury (TBI). Participants were 288 adults with mild complicated, moderate, and severe TBI. Longitudinal data were evaluated during inpatient status in an urban rehabilitation hospital with a TBI Model System, as well as 1 and 2 years post injury. Predictors including demographic characteristics, injury severity, CT characteristics, and neuropsychological evaluations were regressed to outcomes of disability, life satisfaction, and employment at 1 and 2 years post injury. Prediction of life satisfaction was not improved with the use of CT characteristics or neuropsychological tests, but prediction of return to work was improved by these variables at 2 years post injury. Neuropsychological evaluations uniquely contributed to outcome predictions of functional disability, even after considering demographic and injury severity characteristics, including information from CT. In contrast, CT characteristics were not predictive of long-term functional disability at 1 or 2 years post TBI. Taken together, the findings indicate that neuropsychological tests add unique predictive information for long-term functional outcomes after TBI.
本研究评估了神经心理学测试相对于计算机断层扫描 (CT) 在预测中重度创伤性脑损伤 (TBI) 成年人长期结局方面的增量效用。参与者为 288 名轻度复杂、中度和重度 TBI 的成年人。在 TBI 模型系统的城市康复医院住院期间以及受伤后 1 年和 2 年进行了纵向数据分析。将包括人口统计学特征、损伤严重程度、CT 特征和神经心理学评估在内的预测因子回归为残疾、生活满意度和受伤后 1 年和 2 年就业的结果。使用 CT 特征或神经心理学测试并不能提高生活满意度的预测，但是这些变量可以提高受伤后 2 年的工作回归预测。神经心理学评估即使在考虑了人口统计学和损伤严重程度特征（包括 CT 信息）后，也能为功能残疾的预后预测提供独特的贡献。相比之下，CT 特征不能预测 TBI 后 1 年或 2 年的长期功能残疾。综上所述，这些发现表明，神经心理学测试为 TBI 后的长期功能结局提供了独特的预测信息。
