Institute of Genetics, Vetsuisse Faculty, University of Bern, Bern, Switzerland.
PLoS One. 2013;8(2):e55951. doi: 10.1371/journal.pone.0055951. Epub 2013 Feb 5.
The improvement of meat quality and production traits has high priority in the pork industry. Many of these traits show a low to moderate heritability and are difficult and expensive to measure. Their improvement by targeted breeding programs is challenging and requires knowledge of the genetic and molecular background. For this study we genotyped 192 artificial insemination boars of a commercial line derived from the Swiss Large White breed using the PorcineSNP60 BeadChip with 62,163 evenly spaced SNPs across the pig genome. We obtained 26 estimated breeding values (EBVs) for various traits including exterior, meat quality, reproduction, and production. The subsequent genome-wide association analysis allowed us to identify four QTL with suggestive significance for three of these traits (p-values ranging from 4.99×10⁻⁶ to 2.73×10⁻⁵). Single QTL for the EBVs pH one hour post mortem (pH1) and carcass length were on pig chromosome (SSC) 14 and SSC 2, respectively. Two QTL for the EBV rear view hind legs were on SSC 10 and SSC 16.
改善肉质和生产性状是猪肉产业的重中之重。许多这些性状表现出低到中度的遗传力，并且难以测量且成本高昂。通过有针对性的育种计划来改善这些性状具有挑战性，并且需要了解遗传和分子背景。在这项研究中，我们使用 PorcineSNP60 BeadChip 对来自瑞士大白猪的商业品系的 192 头人工授精公猪进行了基因分型，该芯片在猪基因组上均匀分布了 62,163 个 SNP。我们获得了 26 个各种性状的估计育种值（EBV），包括外观、肉质、繁殖和生产。随后的全基因组关联分析使我们能够鉴定出四个对其中三个性状具有提示意义的 QTL（p 值范围从 4.99×10⁻⁶ 到 2.73×10⁻⁵）。与死后 1 小时 pH 值（pH1）和胴体长度的 EBV 相关的单个 QTL 分别位于猪染色体（SSC）14 和 SSC 2 上。与后腿后视 EBV 相关的两个 QTL 分别位于 SSC 10 和 SSC 16 上。
