Diabetes Centre, Northern General Hospital, Sheffield, UK.
Adv Exp Med Biol. 2012;771:51-61. doi: 10.1007/978-1-4614-5441-0_7.
Type 2 diabetes mellitus (a disease normally appears in the post 40 age group people) now seems to emerging in young adults at the level of global epidemic driven by the increasing burden of obesity. Evidence is accumulating to suggest that this young diabetic cohort is an aggressive phenotype which leads to the premature development of complications that not only have impact on the quality of life but also unfavourably influence the long term outcome, raising the possibility of a serious public health challenge in the next few decades. This chapter reviews the current understanding of the phenomenon of T2DM in the young adults and discusses the clinical challenges in managing this high risk group.
2 型糖尿病(一种通常出现在 40 岁以后人群的疾病)现在似乎由于肥胖负担的增加而在全球范围内以流行的方式出现在年轻人中。越来越多的证据表明,这群年轻的糖尿病患者具有侵袭性表型,导致并发症的过早发展,这不仅对生活质量有影响,而且对长期结果也不利,这增加了未来几十年内面临严重公共卫生挑战的可能性。本章回顾了目前对年轻人 2 型糖尿病现象的理解,并讨论了管理这一高危人群的临床挑战。