Diabetes Research Department, University Hospitals of Leicester, UK.
Postgrad Med J. 2010 Dec;86(1022):711-8. doi: 10.1136/pgmj.2010.100917. Epub 2010 Oct 21.
There is an emerging epidemic of type 2 diabetes (T2DM) in younger adults. They represent an extreme phenotype: likely to be obese, lead a sedentary lifestyle, have a strong family history of T2DM, be of black or minority ethnic origin, and come from less affluent socioeconomic groups. An accurate diagnosis of T2DM in younger adults, while essential to guide management, can be challenging even for the experienced diabetologist. Comorbidities such as hypertension, nephropathy and hyperlipidaemia are prevalent in this group, and, despite the lack of longitudinal data, they represent a very high risk group, with a need for aggressive management. This focused review of the epidemiology, aetiology, clinical outcomes, comorbidities and management of younger adults with T2DM will provide the non-specialist with up-to-date insight into the UK's emerging epidemic.
2 型糖尿病（T2DM）在年轻人群中呈流行趋势。他们是极端表型人群：可能肥胖、久坐不动、有 2 型糖尿病的强烈家族史、来自黑人和少数民族、社会经济地位较低。即使对于经验丰富的糖尿病专家来说，准确诊断年轻人群中的 T2DM 对于指导治疗也极具挑战。该人群中高血压、肾病和高脂血症等合并症很常见，尽管缺乏纵向数据，但他们是极高危人群，需要积极治疗。本文将重点回顾 T2DM 年轻患者的流行病学、病因、临床结局、合并症和管理，为非专科医生提供有关英国这一新兴流行疾病的最新见解。
