年轻与不安：Wnt 信号对成体神经发生的调控。
The young and the restless: regulation of adult neurogenesis by Wnt signaling.
机构信息
Department of Psychiatry, Columbia University, New York, NY 10032, USA.
出版信息
Cell Stem Cell. 2013 Feb 7;12(2):139-40. doi: 10.1016/j.stem.2013.01.013.
Abstract
Wnt signaling plays a critical role in developmental and adult neurogenesis. In this issue of Cell Stem Cell, Jang et al. (2013) and Seib et al. (2013) show how age and neuronal activity regulate adult hippocampal neurogenesis by inhibiting or activating, respectively, distinct components of the Wnt signaling machinery.
摘要
Wnt 信号通路在发育和成年神经发生中起着关键作用。在本期《细胞-干细胞》中，Jang 等人（2013）和 Seib 等人（2013）表明，年龄和神经元活性通过分别抑制或激活 Wnt 信号通路的不同成分来调节成年海马神经发生。
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