Gildas Comlan Zohoun Alban, Moket Danièle, El Hamzaoui Sakina
Laboratoire de bactériologie, Hôpital militaire d'instruction Mohammed V, Rabat, Maroc.
Ann Biol Clin (Paris). 2013 Jan-Feb;71(1):27-30. doi: 10.1684/abc.2012.0778.
We studied the production of metallo-β-lactamases (MBL) in Acinetobacter baumannii and Pseudomonas aeruginosa strains resistant to imipenem at the Rabat Mohammed V military teaching hospital, according to Yong et al.'s method, using a sterilized solution of EDTA 0.5 M pH 8. One hundred and five bacterial strains (48 A. baumannii and 57 P. aeruginosa) were identified. 45 (42.9%) with 34 A. baumannii and 11 P. aeruginosa were resistant to imipenem. The prevalence of MBL producing strains was 22.2% (10/45). The existence of this isolates resistant to imipenem by producing metallo-β-lactamases is an emerging public health problem. It is necessary to implemente infection control programs to avoid spreading of multidrug resistant bacteria.
我们在拉巴特穆罕默德五世军事教学医院,根据Yong等人的方法,使用0.5M pH 8的灭菌乙二胺四乙酸(EDTA)溶液,研究了鲍曼不动杆菌和铜绿假单胞菌中对亚胺培南耐药菌株的金属β-内酰胺酶(MBL)产生情况。共鉴定出105株细菌(48株鲍曼不动杆菌和57株铜绿假单胞菌)。其中45株(42.9%)对亚胺培南耐药,包括34株鲍曼不动杆菌和11株铜绿假单胞菌。产MBL菌株的流行率为22.2%(10/45)。这些通过产生金属β-内酰胺酶而对亚胺培南耐药的菌株的存在是一个新出现的公共卫生问题。有必要实施感染控制计划以避免多重耐药菌的传播。