Department of Radiology, University Medical Center Regensburg, Franz-Josef-Strauß-Allee 11, 93053, Regensburg, Germany,
Cardiovasc Intervent Radiol. 2013 Oct;36(5):1288-95. doi: 10.1007/s00270-013-0567-5. Epub 2013 Feb 9.
To determine the feasibility and efficacy of transarterial endoleak embolization using the liquid embolic agent ethylene vinyl alcohol copolymer (Onyx).
Over a 7-year period eleven patients (6 women, 5 men; mean age 68 years, range 37-83 years) underwent transarterial embolization of a type II endoleak after endovascular aortic aneurysm repair using the liquid embolic agent Onyx. Two patients (18 %) had a simple type II endoleak with only one artery in communication with the aneurysm sac, whereas 9 patients (82 %) had a complex type II endoleak with multiple communicating vessels. We retrospectively analyzed the technical and clinical success of transarterial type II endoleak embolization with Onyx. Complete embolization of the nidus was defined as technical success. Embolization was considered clinically successful when volume of the aneurysm sac was stable or decreased on follow-up CT scans.
Mean follow-up time was 26.0 (range 6-50) months. Clinical success was achieved in 8 of 11 patients (73 %). Transarterial nidus embolization with Onyx was technically successful in 6 of 11 patients (55 %). In three cases the nidus was embolized without direct catheterization from a more distal access through the network of collateral vessels.
Onyx is a favorable embolic agent for transarterial endoleak embolization. To achieve the best clinical results, complete occlusion of the nidus is mandatory.
确定使用液体栓塞剂乙烯-乙烯醇共聚物(Onyx)经动脉腔内治疗Ⅱ型内漏的可行性和疗效。
在 7 年期间,11 例患者(6 名女性,5 名男性;平均年龄 68 岁,范围 37-83 岁)在血管内主动脉瘤修复后接受了液体栓塞剂 Onyx 经动脉腔内治疗Ⅱ型内漏。2 例患者(18%)仅有一条动脉与动脉瘤囊相通,为单纯型Ⅱ型内漏,9 例患者(82%)为多发交通支的复杂型Ⅱ型内漏。我们回顾性分析了使用 Onyx 经动脉腔内治疗Ⅱ型内漏的技术和临床效果。完全栓塞瘤巢定义为技术成功。如果动脉瘤囊的体积在随访 CT 扫描中稳定或减小,则栓塞被认为是临床成功的。
平均随访时间为 26.0(范围 6-50)个月。11 例患者中有 8 例(73%)达到临床成功。11 例患者中有 6 例(55%)经动脉腔内 Onyx 瘤巢栓塞技术成功。在 3 例中,通过侧支血管网络从更远端的入路间接导管进入而栓塞瘤巢。
Onyx 是一种用于经动脉腔内治疗Ⅱ型内漏的良好栓塞剂。为了获得最佳的临床效果,必须完全闭塞瘤巢。