Department of Public Health, Weill Cornell Medical College, New York, NY 10065, USA.
Health Serv Res. 2013 Apr;48(2 Pt 2):810-25. doi: 10.1111/1475-6773.12038. Epub 2013 Feb 12.
Provider profiling of outcome performance has become increasingly common in pay-for-performance programs. For chronic conditions, a substantial proportion of patients eligible for outcome measures may be lost to follow-up, potentially compromising outcome profiling. In the context of primary care depression treatment, we assess the implications of missing data for the accuracy of alternative approaches to provider outcome profiling.
We used data from the Improving Mood-Promoting Access to Collaborative Treatment trial and the Depression Improvement across Minnesota, Offering a New Direction initiative to generate parameters for a Monte Carlo simulation experiment.
The patient outcome of interest is the rate of remission of depressive symptoms at 6 months among a panel of patients with major depression at baseline. We considered two alternative approaches to profiling this outcome: (1) a relative, or tournament style threshold, set at the 80th percentile of remission rate among all providers, and (2) an absolute threshold, evaluating whether providers exceed a specified remission rate (30 percent). We performed a Monte Carlo simulation experiment to evaluate the total error rate (proportion of providers who were incorrectly classified) under each profiling approach. The total error rate was partitioned into error from random sampling variability and error resulting from missing data. We then evaluated the accuracy of alternative profiling approaches under different assumptions about the relationship between missing data and depression remission.
Over a range of scenarios, relative profiling approaches had total error rates that were approximately 20 percent lower than absolute profiling approaches, and error due to missing data was approximately 50 percent lower for relative profiling. Most of the profiling error in the simulations was a result of random sampling variability, not missing data: between 11 and 21 percent of total error was attributable to missing data for relative profiling, while between 16 and 33 percent of total error was attributable to missing data for absolute profiling. Finally, compared with relative profiling, absolute profiling was much more sensitive to missing data that was correlated with the remission outcome.
Relative profiling approaches for pay-for-performance were more accurate and more robust to missing data than absolute profiling approaches.
在按绩效付费的项目中,越来越多地对医疗服务提供者的绩效进行分析。对于慢性疾病,大量符合结果评估标准的患者可能会失访,这可能会影响对服务提供者绩效的分析。在基层医疗抑郁治疗的背景下,我们评估了数据缺失对替代方法评估服务提供者绩效准确性的影响。
我们使用了改善情绪促进协作治疗试验(Improving Mood-Promoting Access to Collaborative Treatment trial)和明尼苏达州抑郁改善,提供新方向倡议(Depression Improvement across Minnesota, Offering a New Direction initiative)的数据,为蒙特卡罗模拟实验生成参数。
我们感兴趣的患者结果是基线时患有重度抑郁症的患者中,在 6 个月时抑郁症状缓解的比例。我们考虑了两种替代方法来分析这一结果:(1)相对的,或锦标赛式的阈值,设定在所有提供者缓解率的第 80 百分位数;(2)绝对阈值,评估提供者是否超过规定的缓解率(30%)。我们进行了蒙特卡罗模拟实验,以评估每种分析方法的总错误率(错误分类的提供者比例)。总错误率分为随机抽样变异性造成的错误和数据缺失造成的错误。然后,我们根据缺失数据与抑郁缓解之间的关系的不同假设,评估了替代分析方法的准确性。
在一系列情景中,相对分析方法的总错误率比绝对分析方法低约 20%,相对分析方法的缺失数据造成的错误率低约 50%。模拟中的大部分分析错误是由于随机抽样变异性,而不是数据缺失造成的:对于相对分析,总错误的 11%至 21%归因于缺失数据,而对于绝对分析,总错误的 16%至 33%归因于缺失数据。最后,与相对分析相比,绝对分析对与缓解结果相关的缺失数据更加敏感。
在按绩效付费的情况下,相对分析方法比绝对分析方法更准确,对数据缺失的鲁棒性更强。