Pneumology Department, Clinic Institute of Thorax (ICT), Hospital Clinic of Barcelona, Barcelona 08036, Spain.
Infect Dis Clin North Am. 2013 Mar;27(1):189-203. doi: 10.1016/j.idc.2012.11.009.
Treatment failure in community-acquired pneumonia (CAP) is the failure to normalize the clinical features (eg, fever, cough, sputum production), or nonresolving image in chest radiograph, despite antimicrobial therapy. The incidence of treatment failure in CAP has not been clearly established; according to several studies it ranges between 6% and 15%. The rate of mortality increases significantly, especially in those patients with severe CAP. It is important to be able to identify what patients are at risk for progressive or treatment failure pneumonia that may make them candidates for a more careful monitoring.
治疗社区获得性肺炎 (CAP) 失败是指尽管进行了抗菌治疗，但临床症状（例如，发热、咳嗽、咳痰）或胸部 X 线图像仍未恢复正常。CAP 治疗失败的发生率尚未明确确定；根据几项研究，其范围在 6%至 15%之间。死亡率显着增加，尤其是在那些患有严重 CAP 的患者中。重要的是要能够识别哪些患者有进展性或治疗失败性肺炎的风险，这可能使他们成为更仔细监测的候选者。
