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植入式除颤器与心内膜切除术的手术风险。

Operative risks of the implantable defibrillator versus endocardial resection.

作者信息

Kron I L, Haines D E, Tribble C G, Blackbourne L H, Flanagan T L, Hobson C E, DiMarco J P

机构信息

Department of Surgery, University of Virginia Health Sciences Center, Charlottesville 22908.

出版信息

Ann Surg. 1990 May;211(5):600-3; discussion 603-4.

Abstract

Both map-guided endocardial resection (ER) and the automatic implantable cardioverter defibrillator (AICD) are currently used for surgical treatment of patients who have sustained ventricular tachyarrhythmias. Some authors have preferred AICD implant due to a lower published operative mortality rate. To determine if there is a discrepancy in mortality rates between the two techniques, we analyzed hospital survival in 46 patients undergoing ER and in 44 patients undergoing AICD implantation during the same 3-year period. Two ER patients (4%) died before hospital discharge. Two patients (4%) died after AICD implantation. At predischarge electrophysiologic study five patients (11%) had inducible ventricular tachycardia and received antiarrhythmic drug therapy after ER. In contrast 35 of 42 patients surviving AICD placement received chronic long-term antiarrhythmic therapy (p less than 0.05 compared to ER). Our experience shows that ER and AICD placement may be carried out with similar procedure-related mortality and morbidity rates. Lower operative risks should not be a reason for choosing the AICD over ER for surgical treatment of ventricular tachyarrhythmias. The AICD may actually improve the results of ER by offering an alternative to ventriculotomy in poor-risk surgical candidates.

摘要

地图引导的心内膜切除术(ER)和植入式自动心脏复律除颤器(AICD)目前都用于持续性室性心律失常患者的外科治疗。一些作者因已公布的手术死亡率较低而倾向于植入AICD。为了确定这两种技术在死亡率上是否存在差异,我们分析了在同一3年期间接受ER的46例患者和接受AICD植入的44例患者的住院生存率。2例ER患者(4%)在出院前死亡。2例患者(4%)在植入AICD后死亡。在出院前的电生理研究中,5例患者(11%)诱发出室性心动过速,并在ER后接受了抗心律失常药物治疗。相比之下,42例AICD植入术后存活的患者中有35例接受了长期抗心律失常治疗(与ER相比,p<0.05)。我们的经验表明,ER和AICD植入的手术相关死亡率和发病率可能相似。较低的手术风险不应成为在室性心律失常的外科治疗中选择AICD而非ER的理由。AICD实际上可以通过为手术风险高的患者提供心室切开术的替代方法来改善ER的效果。

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