1st Department of Internal, University Hospital Cologne, Cologne, Germany.
Ann Oncol. 2013 May;24(5):1189-202. doi: 10.1093/annonc/mdt001. Epub 2013 Feb 10.
Cancer patients frequently suffer from gastrointestinal complications. However, a comprehensive, practical and evidence-based guideline on this issue is not yet available.
An expert group was put together by the Infectious Diseases Working Party (AGIHO) of the German Society of Hematology and Oncology (DGHO) to develop a guideline on gastrointestinal complications in cancer patients. For each subtopic, a literature search was carried out in PubMed, Medline and Cochrane databases and the strength of recommendation and the quality of the published evidence for major therapeutic strategies were categorized using a modification of the 'Infectious Diseases Society of America' criteria. Consensus discussions were held on each of the topics.
Recommendations were made with respect to non-infectious and infectious gastrointestinal complications. For all recommendations, the strength of the recommendation and the level of evidence are presented.
This guideline is an evidence-based approach to the diagnosis and management of gastrointestinal complications in cancer patients.
癌症患者常患有胃肠道并发症。然而，目前尚无关于这一问题的全面、实用且基于证据的指南。
德国血液学和肿瘤学会（DGHO）传染病工作组（AGIHO）召集了一个专家组，制定了一份关于癌症患者胃肠道并发症的指南。针对每个子主题，在 PubMed、Medline 和 Cochrane 数据库中进行了文献检索，并使用“美国传染病学会”标准的修改版对主要治疗策略的推荐强度和已发表证据的质量进行了分类。对每个主题都进行了共识讨论。
针对非传染性和传染性胃肠道并发症提出了建议。对于所有建议，均提出了推荐强度和证据水平。
本指南是针对癌症患者胃肠道并发症的诊断和治疗的循证方法。
