Lu Ke, Dong Shanwu, Wu Xiaoyan, Jin Runming, Chen Hongbo
Department of Pediatrics, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Department of Pediatrics, Wuhan Fourth Hospital, Wuhan, China.
Front Oncol. 2021 Mar 12;11:638148. doi: 10.3389/fonc.2021.638148. eCollection 2021.
In recent years, the consumption of over-the-counter probiotics to promote health has grown rapidly worldwide and become an independent industry. In medicine, various studies have demonstrated that probiotics can help improve the immune system and intestinal health. They are usually safe, but in some rare cases, they may cause concerning adverse reactions. Although the use of probiotics has been widely popularized in the public, the results of many probiotic clinical trials are contradictory. Particularly in cancer patients, the feasibility of probiotic management providing benefits by targeting cancer and lessening anticancer side effects requires further investigation. This review summarizes the interactions between probiotics and the host as well as current knowledge on the pros and cons of utilizing probiotics in cancer patients.
近年来，用于促进健康的非处方益生菌在全球范围内的消费量迅速增长，并成为一个独立的产业。在医学领域，各种研究表明，益生菌有助于改善免疫系统和肠道健康。它们通常是安全的，但在某些罕见情况下，可能会引起令人担忧的不良反应。尽管益生菌的使用已在公众中广泛普及，但许多益生菌临床试验的结果相互矛盾。特别是在癌症患者中，通过靶向癌症和减轻抗癌副作用来提供益处的益生菌管理的可行性需要进一步研究。本综述总结了益生菌与宿主之间的相互作用以及目前关于在癌症患者中使用益生菌的利弊的知识。
