Research Center for Insurance Medicine, Amsterdam, The Netherlands.
BMC Public Health. 2013 Feb 12;13:128. doi: 10.1186/1471-2458-13-128.
Screening for mental disorders among disability claimants is important, since mental disorders seem to be seriously under-recognized in this population. However, performance of potentially suitable scales is unknown. We aimed to evaluate the psychometric properties of three scales, the 10- and 6-item Kessler Psychological Distress Scale (K10, K6) and the 12-item General Health Questionnaire (GHQ-12), to predict present state mental disorders, classified according to the Diagnostic and Statistical Manual of Mental Disorders, 4thEdition (DSM-IV) among disability claimants.
All scales were completed by a representative sample of persons claiming disability benefit after two years sickness absence (n=293). All diagnoses, both somatic and mental, were included. The gold standard was the Composite International Diagnostic Interview (CIDI 3.0) to diagnose present state DSM-IV disorder. Cronbach's α, sensitivity, specificity, positive (PPV) and negative predictive values (NPV), and the areas under the Receiver Operating Characteristic curve (AUC) were calculated.
Cronbach's alpha's were 0.919 (K10), 0.882 (K6) and 0.906 (GHQ-12). The optimal cut-off scores were 24 (K10), 14 ( K6) and 20 (GHQ-12). The PPV and the NPV for the optimal cut point of the K10 was 0.53 and 0.89, for the K6 0.51 and 0.87, and for the GHQ-12 0.50 and 0.82. The AUC's for 30-day cases were 0.806 (K10; 95% CI 0.749-0.862), 0.796 (K6; 95% CI 0.737-0.854) and 0.695 (GHQ-12; 95% CI 0.626-0.765).
The K10 and K6 are reliable and valid scales to screen for present state DSM-IV mental disorder. The optimal cut-off scores are 24 (K10) and 14 (K6). The GHQ-12 (optimal cut-off score: 20) is outperformed by the K10 and K6, which are to be preferred above the GHQ-12. The scores on separate items of the K10 and K6 can be used in disability assessment settings as an agenda for an in-depth follow-up clinical interview to ascertain the presence of present state mental disorder.
对残疾索赔者进行精神障碍筛查很重要,因为精神障碍在这一人群中似乎严重未被识别。然而,潜在适用量表的性能尚不清楚。我们旨在评估三种量表的心理测量特性,即 10 项和 6 项 Kessler 心理困扰量表(K10、K6)和 12 项一般健康问卷(GHQ-12),以预测残疾索赔者中根据精神障碍诊断与统计手册,第 4 版(DSM-IV)分类的当前状态精神障碍。
所有量表均由两年病假后申请残疾津贴的代表性人群(n=293)完成。所有诊断,包括躯体和精神诊断,均包括在内。金标准是复合国际诊断访谈(CIDI 3.0),用于诊断当前状态 DSM-IV 障碍。计算了克朗巴赫的 α、敏感性、特异性、阳性(PPV)和阴性预测值(NPV)以及接收器操作特征曲线(ROC)下的面积(AUC)。
K10 的克朗巴赫的α为 0.919,K6 为 0.882,GHQ-12 为 0.906。最佳截断分数为 24(K10)、14(K6)和 20(GHQ-12)。K10 的最佳截断点的 PPV 和 NPV 为 0.53 和 0.89,K6 为 0.51 和 0.87,GHQ-12 为 0.50 和 0.82。30 天病例的 AUC 分别为 0.806(K10;95%CI 0.749-0.862)、0.796(K6;95%CI 0.737-0.854)和 0.695(GHQ-12;95%CI 0.626-0.765)。
K10 和 K6 是筛查当前状态 DSM-IV 精神障碍的可靠有效量表。最佳截断分数为 24(K10)和 14(K6)。GHQ-12(最佳截断分数:20)优于 K10 和 K6,因此优于 GHQ-12。K10 和 K6 的单独项目得分可在残疾评估环境中用作深入随访临床访谈的议程,以确定当前状态精神障碍的存在。