Fornari M, Solero C L, Lasio G, Lodrini S, Balestrini M R, Cimino C, Visintini S, Pluchino F
Department of Neurosurgery, Istituto Neurologico C. Besta, Milan, Italy.
Childs Nerv Syst. 1990 Mar;6(2):66-70. doi: 10.1007/BF00307923.
Between 1956 and 1987 operations were performed on 36 patients below the age of 20 years for epidermoid and dermoid cysts of the central nervous system. Seventeen tumors were intracranial intradural lesions (47%): 12 were located in the supratentorial region (71%) and 5 were located in the infratentorial region (29%). Ten of these tumors (59%) were seated along the midline structures. The clinical presentation was consistent with the location of the tumors. The neuroradiological diagnosis was mostly made with the aid of pneumoencephalography, computed tomography (CT), nonionic contrast medium CT cisternography, and magnetic resonance imaging. Complete removal of the tumor contents was performed in all cases but one, although the completeness of removal of the tumor capsule could not be exactly estimated in some patients. At late follow-up only two tumor recurrences were observed. Radical removal of the tumor capsule of these congenital tumors, even when it is connected to vital neurovascular structures, seems advisable in patients who become symptomatic within the first two decades of life.
1956年至1987年间,对36例20岁以下患有中枢神经系统表皮样囊肿和皮样囊肿的患者进行了手术。17例肿瘤为颅内硬膜内病变(47%):12例位于幕上区域(71%),5例位于幕下区域(29%)。其中10例肿瘤(59%)位于中线结构。临床表现与肿瘤位置相符。神经放射学诊断主要借助气脑造影、计算机断层扫描(CT)、非离子造影剂CT脑池造影和磁共振成像。除1例患者外,所有病例均完整切除了肿瘤内容物,不过部分患者的肿瘤包膜切除完整性无法准确评估。在晚期随访中,仅观察到2例肿瘤复发。对于在生命的前二十年出现症状的患者,即使这些先天性肿瘤的包膜与重要神经血管结构相连,彻底切除肿瘤包膜似乎也是可取的。