从越南中华蜜蜂分离出的囊状幼虫病毒株SBM2的全基因组序列
Complete Genome Sequence of Sacbrood Virus Strain SBM2, Isolated from the Honeybee Apis cerana in Vietnam.
作者信息
Nguyen Nga Thi Bich, Le Thanh Hoa
机构信息
Immunology Department, Institute of Biotechnology, Vietnam Academy of Science and Technology (VAST), Hanoi, Vietnam.
出版信息
Genome Announc. 2013 Jan;1(1). doi: 10.1128/genomeA.00076-12. Epub 2013 Jan 31.
Abstract
Here we report the complete genomic sequence of the SBM2 strain (VSBV-SBM2) of the sacbrood virus (SBV) that was isolated from the Asian honeybee (Apis cerana) in Northern Vietnam. The entire sequence excluding the 3' poly(A) tail is 8,834 nucleotides in length and contains a single large open reading frame (ORF) of 8,580 nucleotides (position 178 to 8757), encoding 2,859 amino acids. VSBV-SBM2 shared 90 to 93% nucleotide identity and 95 to 96% amino acid homology to six complete genomes of SBV currently available in GenBank (two from China, three from Korea, and one from the United Kingdom). A hypervariable domain (amino acid [aa] position 712 to 729) and a conserved motif (position 2124 to 2143) in the precursor polypeptide of all seven SBVs are also described.
摘要
在此，我们报告了从越南北部的亚洲蜜蜂（中华蜜蜂）中分离出的囊状幼虫病毒（SBV）的SBM2株（VSBV-SBM2）的完整基因组序列。除去3' 聚腺苷酸尾后的整个序列长度为8834个核苷酸，包含一个8580个核苷酸的单一大型开放阅读框（ORF）（位置178至8757），编码2859个氨基酸。VSBV-SBM2与GenBank中目前可用的六个SBV完整基因组具有90%至93%的核苷酸同一性和95%至96%的氨基酸同源性（两个来自中国，三个来自韩国，一个来自英国）。还描述了所有七个SBV的前体多肽中的一个高变域（氨基酸[aa]位置712至729）和一个保守基序（位置2124至2143）。
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