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偏头痛与认知衰退:专题述评。

Migraine and cognitive decline: a topical review.

机构信息

Division of Preventive Medicine, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.

出版信息

Headache. 2013 Apr;53(4):589-98. doi: 10.1111/head.12046. Epub 2013 Feb 13.

Abstract

Migraine has been linked with an increased risk of stroke and an increased prevalence of clinically silent brain lesions and white-matter hyperintensities. As it is known that stroke and structural brain lesions are associated with an increased risk of cognitive decline, it has been hypothesized that migraine may be a progressive brain disorder and associated with an increased risk of cognitive impairment. Given the prevalence of migraine in the population, especially among women, and the aging of the population, an association between migraine and cognitive impairment would have substantial public health implications. In this review, we will summarize the existing evidence evaluating the association between migraine and cognitive function. Additionally, we will discuss methodological issues in migraine and cognitive function assessment and elaborate on study design strategies to address this important question.

摘要

偏头痛与中风风险增加、临床无症状性脑损伤和脑白质高信号相关。由于已知中风和结构性脑损伤与认知能力下降风险增加相关,因此有人假设偏头痛可能是一种进行性脑疾病,与认知障碍风险增加相关。鉴于偏头痛在人群中的普遍存在,尤其是在女性中,以及人口老龄化,偏头痛与认知障碍之间的关联将具有重大的公共卫生意义。在这篇综述中,我们将总结评估偏头痛与认知功能之间关联的现有证据。此外,我们还将讨论偏头痛和认知功能评估中的方法学问题,并详细阐述解决这一重要问题的研究设计策略。

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Migraine and cognitive decline: a topical review.偏头痛与认知衰退:专题述评。
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本文引用的文献

1
Structural brain changes in migraine.偏头痛的大脑结构变化。
JAMA. 2012 Nov 14;308(18):1889-97. doi: 10.1001/jama.2012.14276.
3
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