1Centre for Health Services and Nursing Research, and Department of Public Health and Primary Care, KU Leuven, Belgium.
Eur J Cardiovasc Nurs. 2013 Oct;12(5):475-83. doi: 10.1177/1474515113477955. Epub 2013 Feb 13.
Since survival rates of patients with congenital heart disease (CHD) have improved, issues beyond the quantity of life have become more important. Quality of life (QOL) has mainly been investigated in adults with CHD. Hence, research about QOL among adolescents with CHD is much needed.
To compare the QOL of adolescents with CHD with that of control subjects from the general population and to explore whether sense of coherence (SOC) explains differences in QOL between patients and controls.
In this cross-sectional, comparative study, we included 429 patients (229 boys; 200 girls) aged 14-18 years, who were matched to control subjects for age and sex. QOL was measured with a Linear Analogue Scale; SOC was measured using the SOC-13.
Median QOL score in patients was 82 (Q1=75; Q3=90). The QOL of patients was significantly (Z=-5.888; p<0.001) better than that of controls (median=80; Q1=70; Q3=85.5). Adjusted for other potentially confounding factors, linear mixed modelling showed that the better QOL in patients was explained by a higher SOC (mean=61.4±12.0 vs. 53.6±10.4) and better perceived physical health (mean=87.0±13.8 vs. 85.3±13.2).
This study found that adolescents with CHD have a good QOL, one that is better than that of control subjects from the general population. A stronger SOC and better perceived physical health are potential resources for better QOL in patients.
由于先天性心脏病（CHD）患者的生存率有所提高，因此生命数量以外的问题变得更加重要。生活质量（QOL）主要在成人 CHD 患者中进行研究。因此，非常需要研究 CHD 青少年的 QOL。
比较 CHD 青少年与普通人群对照者的 QOL，并探讨心理一致感（SOC）是否可以解释患者与对照者 QOL 之间的差异。
在这项横断面、对照研究中，我们纳入了 429 名年龄在 14-18 岁的患者（229 名男性；200 名女性），并按年龄和性别与对照者匹配。使用线性模拟量表测量 QOL；使用 SOC-13 量表测量 SOC。
患者的 QOL 中位数为 82（Q1=75；Q3=90）。患者的 QOL 明显（Z=-5.888；p<0.001）优于对照者（中位数=80；Q1=70；Q3=85.5）。在调整其他潜在混杂因素后，线性混合模型显示，患者更好的 QOL 可由更高的 SOC（均值=61.4±12.0 与 53.6±10.4）和更好的感知身体健康状况（均值=87.0±13.8 与 85.3±13.2）来解释。
本研究发现，CHD 青少年的 QOL 良好，优于普通人群对照者。更强的 SOC 和更好的感知身体健康状况是患者更好 QOL 的潜在资源。
