将直肠内磁共振弹性成像纳入前列腺癌多参数 MRI 成像：志愿者初步可行性研究。
Incorporating endorectal MR elastography into multi-parametric MRI for prostate cancer imaging: Initial feasibility in volunteers.
机构信息
Physical Sciences, Sunnybrook Research Institute, Toronto, Ontario, Canada; Department of Medical Biophysics, University of Toronto, Toronto, Ontario, Canada.
出版信息
J Magn Reson Imaging. 2013 Nov;38(5):1251-60. doi: 10.1002/jmri.24028. Epub 2013 Feb 13.
PURPOSE
To investigate the tolerability and technical feasibility of performing endorectal MR elastography (eMRE) in human volunteers within the representative age group commonly affected by prostate cancer.
MATERIALS AND METHODS
Endorectal MRE was conducted on seven volunteers in a 1.5 Tesla (T) MR imager using a rigid endorectal coil. Another five volunteers were imaged on a 3T MR imager using an inflatable balloon type endorectal coil. Tolerability was accessed for vibration amplitudes of ±1-50 μm and for frequencies of 100-300 Hz.
RESULTS
All 12 volunteers tolerated the displacements necessary to successfully perform eMRE. Shear waves with frequencies up to 300 Hz could propagate across the entire prostate using both coil designs.
CONCLUSION
The results of this study motivate further investigation of eMRE in prostate cancer patients to help determine if there is an added value of integrating eMRE into existing multi-parametric prostate MRI exams.
目的
在常见前列腺癌发病年龄段的志愿者中，研究直肠内磁共振弹性成像（eMRE）的耐受性和技术可行性。
材料和方法
在 1.5T 磁共振成像仪上使用刚性直肠内线圈对 7 名志愿者进行直肠内 MRE 检查。另外 5 名志愿者在 3T 磁共振成像仪上使用充气式球囊型直肠内线圈进行成像。评估了±1-50μm 的振动幅度和 100-300Hz 的频率的耐受性。
结果
所有 12 名志愿者都能耐受成功进行 eMRE 所需的位移。两种线圈设计均能在整个前列腺中传播频率高达 300Hz 的剪切波。
结论
本研究结果激励了进一步在前列腺癌患者中进行 eMRE 的研究，以帮助确定将 eMRE 整合到现有的多参数前列腺 MRI 检查中是否具有附加价值。
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