Ruiz B C, Tucker W K, Kirby R R
Anesthesiology. 1975 Jan;42(1):88-95. doi: 10.1097/00000542-197501000-00013.
With a desk-top, programmable calculator, it is now possible to do complex, previously time-consuming computations in the blood-gas laboratory. The authors have developed a program with the necessary algorithms for temperature correction of blood gases and calculation of acid-base variables and intrapulmonary shunt. It was necessary to develop formulas for the Po2 temperature-correction coefficient, the oxyhemoglobin-dissociation curve for adults (withe necessary adjustments for fetal blood), and changes in water vapor pressure due to variation in body temperature. Using this program in conjuction with a Monroe 1860-21 statistical programmable calculator, it is possible to temperature-correct pH,Pco2, and Po2. The machine will compute alveolar-arterial oxygen tension gradient, oxygen saturation (So2), oxygen content (Co2), actual HCO minus 3 and a modified base excess. If arterial blood and mixed venous blood are obtained, the calculator will print out intrapulmonary shunt data (Qs/Qt) and arteriovenous oxygen differences (a minus vDo2). There also is a formula to compute P50 if pH,Pco2,Po2, and measured So2 from two samples of tonometered blood (one above 50 per cent and one below 50 per cent saturation) are put into the calculator.
借助台式可编程计算器，现在可以在血气实验室进行复杂的、以前耗时的计算。作者开发了一个程序，其中包含用于血气温度校正以及酸碱变量和肺内分流计算的必要算法。有必要为氧分压温度校正系数、成人氧合血红蛋白解离曲线（对胎儿血液进行必要调整）以及体温变化引起的水蒸气压力变化推导公式。将此程序与门罗1860 - 21统计可编程计算器结合使用，可以对pH值、二氧化碳分压和氧分压进行温度校正。该机器将计算肺泡 - 动脉氧分压差、氧饱和度（So2）、氧含量（Co2）、实际碳酸氢根减去3以及修正碱剩余。如果获取了动脉血和混合静脉血，计算器将打印出肺内分流数据（Qs/Qt）和动静脉氧差（a减去vDo2）。如果将来自两个校准血液样本（一个饱和度高于50%，一个低于50%）的pH值、二氧化碳分压、氧分压和测得的So2输入计算器，还有一个用于计算P50的公式。
