Räsänen J, Downs J B, Malec D J, DeHaven B, Seidman P
Department of Anesthesiology, College of Medicine, Ohio State University, Columbus 43210-1228.
Ann Surg. 1987 Nov;206(5):621-3. doi: 10.1097/00000658-198711000-00011.
Total body oxygen utilization coefficient was estimated using continuous pulse and pulmonary artery oximetry (dual oximetry) in 17 patients with respiratory failure. Change in arterial and mixed venous oxygen saturations was induced by altering airway pressure. Continuous measurement of mixed venous oxygen saturation provided an accurate and linear estimate of oxygen utilization coefficient (r = -0.92), the true values being overestimated by 0.05 +/- 0.06 (mean +/- SD). Addition of pulse oximetry improved the correlation (r = 0.93) and decreased the difference between absolute values (0.02 +/- 0.06). Oxygen utilization coefficient can be estimated reliably in an online fashion using pulmonary artery oximetry. However, the use of dual oximetry will further improve the estimate.
在17例呼吸衰竭患者中,使用连续脉搏血氧饱和度测定法和肺动脉血氧饱和度测定法(双血氧饱和度测定法)估算全身氧利用系数。通过改变气道压力来诱导动脉血氧饱和度和混合静脉血氧饱和度的变化。连续测量混合静脉血氧饱和度可对氧利用系数进行准确且呈线性的估算(r = -0.92),真实值被高估0.05±0.06(平均值±标准差)。添加脉搏血氧饱和度测定法可改善相关性(r = 0.93)并减小绝对值之间的差异(0.02±0.06)。使用肺动脉血氧饱和度测定法能够以在线方式可靠地估算氧利用系数。然而,使用双血氧饱和度测定法将进一步改善估算结果。